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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

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Mechanical behaviour of biopolymer scaffolds elucidated by numerical modelling

Anisotropy map
Finite element simulation is proposed to shed more light on 3D elasticity of biopolymer scaffolds at extreme low density. All possibilities of fibrous arrangement in the scaffold are screened and related mechanical behaviour is revealed.

The numerical model is able to control the orientation and density of the fibres at the nanoscale. This model demonstrates a marked anisotropy of behaviour of these airy structures. It reveals the nature of anisotropy inferred to gelatin scaffolds processed using electrospinning with a rotating collector.

Partnerships :

This project is realized within the framework of international mobility funded by the France Embassy, the CEPIA department and Churchill College of Cambridge University, UK. The presented results reflect collaboration between BIA unit and bioengineering laboratory at the University of Cambridge, UK.

References :

Sofiane Guessasma, Michelle Oyen, Virtual design of electrospun-like gelatin scaffolds: role of three-dimensional fibre orientation on elasticity behaviour, Soft Matter, 12 (2016), 602-613.
Sofiane Guessasma, Michelle Oyen, Oliver Armitage, Hedi Nouri, Sensing mechanical performance of electrospun scaffolds using finite element computation and digital image correlation, Engineering mechanics Institute Conference EMI2015, MS 13: Mechanics of Soft Materials and Structures, Stanford university, USA, June 16-19, 2015.