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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

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Richard SIBOUT

Research Scientist, PhD

Plant cell wall and polymers (PVPP)

Contact details

Richard Sibout-2018-10-01

Richard Sibout obtained a PhD in Forest Biology from Université Laval (Canada) under the scientific direction of Dr. Armand Séguin and Prof. John Mackay in 2005. After a short stay at McGill University in Montreal, he did a postdoctoral fellowship at the University of Lausanne in Switzerland in the team of Prof. Christian Hardtke.  In 2011, he took over the leadership of the research team “Paroi secondaire” until then led by Lise Jouanin on the INRA Centre in Versailles.
Since February 2018, Richard Sibout has been a research fellow in the PVPP team of the BIA Unit in Nantes. As a biologist specialized in Brachypodium genomics (a model plant for grasses) and in the comprehension of plant cell wall formation, particularly the lignification mechanisms, he is currently studying the parameters inherent in ligno-cellulosic biomass that control the deconstruction of plant cell walls. 

Fields of practice:

  • Biochemistry of plant walls
  • Genomics of grasses

Scientific publications:

Research articles

Poursarebani N, Trautewig C, Melzer M, Nussbaumer T, Lundqvist U, Rutten T, Schmutzer T, Brandt R, Himmelbach A, Altschmied L, et al. 2020. COMPOSITUM 1 contributes to the architectural simplification of barley inflorescence via meristem identity signals. Nat Commun 11(1): 5138.

Perkins ML, Schuetz M, Unda F, Smith RA, Sibout R, Hoffmann NJ, Wong DCJ, Castellarin SD, Mansfield SD, Samuels L. 2020. Dwarfism of high-monolignol Arabidopsis plants is rescued by ectopic LACCASE overexpression. Plant Direct 4(9): e00265.

Perkins ML, Schuetz M, Unda F, Smith RA, Sibout R, Hoffmann NJ, Wong DCJ, Castellarin SD, Mansfield SD, Samuels L. 2020. Dwarfism of high-monolignol Arabidopsis plants is rescued by ectopic LACCASE overexpression. Plant Direct 4(9): e00265.

Bohrer M, Rymen B, Himber C, Gerbaud A, Pflieger D, Laudencia-Chingcuanco D, Cartwright A, Vogel J, Sibout R, Blevins T. 2020. Integrated Genome-Scale Analysis and Northern Blot Detection of Retrotransposon siRNAs Across Plant Species. Methods in molecular biology 2166: 387-411.

Coomey JH, Sibout R, Hazen SP (2020) Grass secondary cell walls, Brachypodium distachyon as a model for discovery. New Phytol. doi:10.1111/nph.16603

Magne K, Liu S, Massot S, Dalmais M, Morin H, Sibout R, Bendahmane A, Ratet P (2020) Roles of BdUNICULME4 and BdLAXATUM-A in the non-domesticated grass Brachypodium distachyon. Plant J. doi:10.1111/tpj.14758

Woods DP, Dong Y, Bouche F, Mayer K, Varner L, Ream TS, Thrower N, Wilkerson C, Cartwright A, Sibout R, Laudencia-Chingcuanco D, Vogel J, Amasino RM (2020) Mutations in the predicted DNA polymerase subunit POLD3 result in more rapid flowering of Brachypodium distachyon. New Phytol. doi:10.1111/nph.16546

Le Bris P, Wang Y, Barbereau C, Antelme S, Cezard L, Legee F, D'Orlando A, Dalmais M, Bendahmane A, Schuetz M, et al. 2019. Inactivation of LACCASE8 and LACCASE5 genes in Brachypodium distachyon leads to severe decrease in lignin content and high increase in saccharification yield without impacting plant integrity. Biotechnol Biofuels 12: 181.

Yi Chou E, Schuetz, M, Hoffmann, N, Watanabe, Y, Sibout, R and Samuels, AL (2018) Distribution, Mobility and Anchoring of Lignin-Related Oxidative Enzymes in Arabidopsis Secondary Cell Walls. J Exp Bot. DOI /10.1093/jxb/ery067

Voxeur A, Soubigou-Taconnat L, Legée F, Sakai K, Durand-Tardif M, Lapierre C, Sibout R. A defect in the RG-II dimerisation impacts on lignification and xylem formation (2017). PlosOne,

Sibout, R. (2017) Crop breeding: Turning a lawn into a field. Nat Plants, 3, 17060.

Sibout R, Proost S, Hansen BO, Vaid N, Giorgi FM, Ho-Yue-Kuang S, Legée L, Cézart L, Bouchabké-Coussa O, Soulhat C, Lebris P, Roujol D, Hofte H, Jamet E , Lapierre C, Persson S, Mutwil M. (2017) Expression atlas and comparative co-expression network analyses reveal important genes involved in the formation of lignified cell wall in Brachypodium distachyon. New Phytol. 215(3):1009-1025.

Karlen DS, Zhang C, Peck ML, Smith RA, Padmakshan D, Helmich KE, Free HCA, Lee S, Smith BG, Lu F, Sedbrook JC, Sibout R, Grabber JH, Runge TM, Mysore KS, Harris PJ, Bartley LE, Ralph J (2016). Monolignol ferulate conjugates are naturally incorporated into plant lignins. Sci Adv. 2 (10), e1600393

Sibout R, Le Bris P, Legée F, Cézard L, Renault H, Lapierre C (2016). Structural Redesigning Arabidopsis Lignins into Alkali-Soluble Lignins through the Expression of p-Coumaroyl-CoA:Monolignol Transferase PMT. Plant Physiol. 170(3):1358-66.

Ho-Yue-Kuang S, Alvarado C, Antelme S, Bouchet B, Cézard L, Le Bris P, Legée F, Maia-Grondard A, Yoshinaga A, Saulnier L, Guillon F, Sibout R, Lapierre C, Chateigner-Boutin AL. (2016).Mutation in Brachypodium caffeic acid O-methyltransferase 6 alters stem and grain lignins and improves straw saccharification without deteriorating grain quality. J Exp Bot. 67(1):227-37.

Francin-Allami M, Merah K, Albenne C, Rogniaux H, Pavlovic M, Lollier V, Sibout R, Guillon F, Jamet, E and Larre C (2015) Cell wall proteomic of Brachypodium distachyon grains: A focus on cell wall remodeling proteins. Proteomics. 15(13):2296-306

Granier F., Lemaire A., Wang Y., LeBris P., Antelme S., Vogel J. , Laudencia-Chingcuanco D., Sibout R. (2015) Chemical and Radiation Mutagenesis: Induction and Detection by Whole Genome Sequencing. Genetics and Genomics of Brachypodium, Plant Genetics and Genomics: Crops and Models. Volume 18 (Eds J. Vogel), Springer

Wang Y, Bouchabké-Coussa O, Le Bris P, Antelme S, Soulhat C, Gineau E, Dalmais M, Bendahmane A, Morin H, Mouille G, Legée F, Cézard L, Lapierre C, Sibout R (2015). LACCASE 5 is required for lignification of the Brachypodium distachyon culm. Plant Physiol. 2015 May;168(1):192-204

Voxeur A, Wang Y, Sibout R (2015). Lignification: different mechanisms for a versatile polymer. Curr. Opinion Plant Biol. 23: 83-90

Dobrovolskaya O, Pont C, Sibout R, Martinek P, Badaeva E, Murat F, Chosson A, Watanabe N, Prat E,  Gautier N, Gautie V, Poncet C, Orlov Y, Krasnikov A, Bergès H, Salina E, Laikova L, Salse J (2015). FRIZZY PANICLE drives supernumerary spikelets in bread wheat 1 (T. aestivum L.). Plant Physiol. 167: 189-99.

Marriott, P.E., Sibout, R., Lapierre, C., Fangel, J.U., Willats, W.G., Hofte, H., Gomez, L.D. and McQueen-Mason, S.J. (2014) Range of cell-wall alterations enhance saccharification in Brachypodium distachyon mutants. Proc Natl Acad Sci U S A, 111, 14601-14606.

Timpano H, Sibout R, Devaux MF, Alvarado C, Looten R, Falourd X, Pontoire B, Martin M, Legée F, Cézard L, Lapierre C, Badel E, Citerne S, Vernhettes S, Höfte H, Guillon H, Gonneau M (2014). Brachypodium Cell Wall Mutant with Enhanced Saccharification Potential Despite Increased Lignin Content. Bioenerg. Res. DOI 10.1007/s12155-014-9501-1

Girin, T, David LC, Chardin C, Sibout R, Krapp A, Ferrario-Méry S and Daniel-Vedele F (2014). Brachypodium: a promising hub between model species and Cereals. Journal of Experimental Botany. doi:10.1093/jxb/eru376

Petrik DL, Karlen SD, Cass CL, Padmakshan D, Lu F, Liu S, Le Bris P, Antelme S, Santoro N, Wilkerson CG, Sibout R, Lapierre C, Ralph J, Sedbrook JC (2014). p-Coumaroyl-CoA:monolignol transferase (PMT) acts specifically in the lignin biosynthetic pathway in Brachypodium distachyon. Plant J. 77:713-26.

Dalmais M, Antelme S, Ho-Yue-Kuang S, Wang Y, Darracq O, Bouvier d’Yvoire M, Cézard L, Légée F, Blondet E, Oria N, Troadec C, Brunaud V, Jouanin L, Höfte H, Bendahmane A, Lapierre C, Sibout R (2013). A TILLING Platform for Functional Genomics in Brachypodium distachyon. Plos One. 8: e65503.

Wang Y, Chantreau M, Sibout R, Hawkins S (2013). Plant cell wall lignification and monolignol metabolism. Front Plant Sci. 4 : 220.

Bouvier d'Yvoire M, Bouchabke-Coussa O, Voorend W, Antelme S, Cezard L, Legee, F,  Lebris, P, Legay, S, Whitehead, C, McQueen-Mason, S J, Gomez, L D, Jouanin, L, Lapierre, C, Sibout, R (2013). Disrupting the cinnamyl alcohol dehydrogenase 1 gene (BdCAD1) leads to altered lignification and improved saccharification in Brachypodium distachyon. Plant J. 73: 496-508.

Harrington, M.J., Mutwil, M., Barriere, Y. and Sibout, R (2012). Molecular biology of lignification in grasses. In Lignins: Biosynthesis, biodegradation and bioengineering. Advances in Botanical Research (Jouanin, L. and Lapierre, C. eds). Academic Press.

Sibout R, Hofte H (2012). Plant cell biology: the ABC of monolignol transport. Curr. Biol. : CB 22: R533-535.

Ragni L, Nieminen K, Pacheco-Villalobos D, Sibout R, Schwechheimer C, Hardtke CS (2011). Mobile gibberellin directly stimulates Arabidopsis hypocotyl xylem expansion. Plant Cell. 23(4):1322-36

Brkljacic J, Grotewold E, Scholl R, Mockler T, Garvin DF, Vain P, Brutnell T, Sibout R, Bevan M, Budak H, Caicedo AL, Gao C, Gu Y, Hazen SP, Holt BF 3rd, Hong SY, Jordan M, Manzaneda AJ, Mitchell-Olds T, Mochida K, Mur LA, Park CM, Sedbrook J, Watt M, Zheng SJ, Vogel JP (2011). Brachypodium as a model for the grasses: today and the future. Plant Physiol. 157: 3-13.

Vogel et al., The International Brachypodium Initiative (2010). Genome sequencing and analysis of the model grass Brachypodium distachyon. Nature 11:763-8

Sanchez-Rodriguez C, Rubio-Somoza I, Sibout R and Persson S. (2010). Phytohormones and the cell wall in Arabidopsis during seedling growth. Trends Plant sci. Vol.15 : pp. 291-301 

Sibout R, Plantegenet S and Hardtke CS (2008) Flowering as a condition for xylem expansion in Arabidopsis hypocotyl and root. Curr. Biol. 18: 458-463

Do CT, Pollet B, Thevenin J, Sibout R, Denoue D, Barriere Y, Lapierre C, Jouanin L (2007). Both caffeoyl Coenzyme A 3-O-methyltransferase 1 and caffeic acid O-methyltransferase 1 are involved in redundant functions for lignin, flavonoids and sinapoyl malate biosynthesis in Arabidopsis. Planta 226(5): 117-129

Hardtke CS, Dorcey E, Osmont KS, Sibout R (2007). Phytohormone collaboration: zooming in on auxin-brassinosteroid interactions. Trends Cell Biol. 17(10): 485-492

Osmont K, Sibout R, Hardtke CS (2007). Hidden branches: developments in root system architecture. Annu. Rev. Plant Biol. 58: 93-113.

Sibout R, Sukumar P, Hettiarachchi C, Holm M, Muday GK, Hardtke CS (2006). Opposite root growth phenotypes of hy5 versus hy5 hyh mutants correlate with increased constitutive auxin signaling. Plos Genetics 2 : 1898-1911, e202

Briggs G, Osmont K, Shindo C, Sibout R, Hardtke CS (2006). Unequal genetic redundancies in Arabidopsis – a neglected phenomenon ? Trends Plant Sci. 11(10): 492-498

Eudes A, Pollet B, Sibout R, Do CT, Seguin A, Lapierre C, Jouanin L. (2006). Evidence for a role of AtCAD 1 in lignification of elongating stems of Arabidopsis thaliana. Planta 225(1) : 23-29.

Sibout R, Eudes A, Mouille G, Pollet B, Lapierre C, Jouanin L, Séguin A (2005). CINNAMYL ALCOHOL DEHYDROGENASE -C and -D are the primary genes involved in lignin biosynthesis in the floral stem of Arabidopsis. Plant Cell 17: 2059-2076.

Jouanin, L.,  Goujon, T., Sibout, R., Pollet, B., Mila, I., Leplé, J.-C., Pilate, G., Petit-Conil, M., Ralph, J., Lapierre, C. (2004). Comparison of the consequences on lignin content and structure of COMT and CAD downregulation in poplar and Arabidopsis thaliana. In : Christian Walter , Mike Carson , Plantation Forest Biotechnology for the 21st Century. Trivandrum (IND) : Research Signpost. 219-229

Sibout R, Eudes A, Pollet B, Goujon T, Mila I, Granier F, Séguin A, Lapierre C, Jouanin L (2003). Expression pattern of two paralogs encoding cinnamyl alcohol dehydrogenases in Arabidopsis. Isolation and characterization of the corresponding mutants. Plant Physiol. 132: 848-860

Goujon T, Sibout R, Eudes A, MacKay J, Jouanin L (2003). Genes involved in the biosynthesis of lignin precursors in Arabidopsis thaliana. Plant Physiol. Biochem. 41: 677-687

Goujon T, Sibout R, Pollet B, Maba B, Nussaume L, Bechtold N, Lu FC, Ralph J, Mila I, Barriere Y, Lapierre C, Jouanin L (2003). A new Arabidopsis thaliana mutant deficient in the expression of O-methyltransferase impacts lignins and sinapoyl esters. Plant Mol. Biol. 51 (6): 973-989

Sibout R, Baucher M, Gatineau M, Van Doorsselaere J, Mila I, Pollet B, Maba B, Pilate G, Lapierre C, Boerjan W, Jouanin L (2002). Expression of a poplar cDNA encoding a ferulate-5-hydroxylase/coniferaldehyde 5-hydroxylase increases S lignin deposition in Arabidopsis thaliana. Plant Physiol. Biochem. 40 (12): 1087-1096

Sibout R, Guerrier G (1998). Solute incompatibility with glutamine synthetase in water-stressed Populus nigra. Environ Exp. Bot. 40 (2): 173-178