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Dernière mise à jour : Mai 2018

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Larramendy Stéphanie

Team PEP'S

Larramendy Stéphanie
PhD student

Stéphanie Larramendy (who has a dual training as an Agricultural Engineer and a Doctor) is already in professional activity (Head of the University Clinic at the Department of General Medicine of the Faculty of Nantes, and general practitioner in a private practice). She conducts her thesis work concomitantly with her other activities.

Thesis

Territorial and collective determinants of community-acquired BLSE infections.

Supervised by: François Beaudeau.

The general objective of the thesis is, using a "One Health" approach, to identify and quantify the impact of territorial factors associated with an increased risk of E. coli infection that produce ESBLs on community health. The hypothesis explored is that the risk of infection by ESBL-producing bacteria depends on characteristics related to the individual and his/her lifestyle (socio-demographics, type of professional and leisure activities, care pathway, level of exposure to pets, etc.), but also on the characteristics of the territory in which the individual lives (existence of a health care institution, density of doctors and veterinarians, density of human population, animal densities, main agricultural activity in the territory, quantity of antibiotics prescribed in the territory in human and veterinary medicine).

In order to achieve this objective, two aspects are being carried out in parallel: aspect 1/ A systematic review of the literature on the risk factors for contracting an E.coli BLSE urinary tract infection outside the hospital context; aspect 2/ The use of existing databases to identify the characteristics of areas at risk of high prevalence of E.coli BLSE urinary tract infections.

Publications
  • Larramendy S., Deglaire V., Dusollier P., Fournier J. P., Caillon, J., Beaudeau F., Moret L. 2020. Risk factors of extended-spectrum beta-lactamases-producing Escherichia coli community-acquired urinary tract infections: a systematic review. Infection and Drug Resistance, Accepté [IF19=2.984]
  • Larramendy S., Gaultier A., Giffon S., Thibaut S., Caillon J., Moret L., Beaudeau F. 2020. Prevalence of extended-spectrum beta-lactamase-producing Escherichia coli in community-acquired urinary tract infections in Western France. Médecine et Maladies Infectieuses, 50(3):297-300 [IF19=1.782] DOI: 10.1016/j.medmal.2019.09.0