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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

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Meurens François

Team ImmunoCare

Meurens François
© FM

Professor of Microbiology/Immunology DGER

 Oniris site de la Chantrerie, CS40706, 44307 Nantes, France
 team ImmunoCare, building G5 2nd floor

Email: francois (point) meurens(at) oniris-nantes (point) fr
Tel: 02 40 68 77 02

François Meurens studied veterinary medicine in Belgium (Université Catholique de Louvain and Université de Liège) where he graduated in 2000. In 2001, he obtained his Master's degree in Veterinary Sciences (virology orientation) and in 2004 he completed his PhD thesis in Veterinary Sciences after studying genetic recombination in ruminant alphaherpesviruses (Laboratory of Professor Etienne Thiry). He then did a post-doctorate at VIDO-InterVac at the University of Saskatchewan (Canada) for two years. There he was interested in mucosal immunology in porcine and ovine species (laboratory of Pr Volker Gerdts).

At the end of 2006 he joined the INRA of Tours (ISP unit) as a research fellow. There he led a team specialized in the study of host-pathogen relationships in the porcine model. In 2012 he accepted a position as a Scientist/Assistant Professor at VIDO-InterVac (Canada) where he led a team on themes very similar to those developed in France. Particular attention was paid to the interest of the pig as a model species for human biomedical research. Author of numerous publications in international peer-reviewed journals and working as an expert for the private sector and on the editorial boards of the journals Veterinary Immunology and Immunopathology and Frontiers in Veterinary Medicine, Dr. Meurens has moved in 2015 towards a more academic career combining teaching and scientific research at Oniris. Since then, he has been teaching microbiology/immunology and conducting research within the UMR BioEpAR.

  • Ao D., Li S., Jiang S., Luo J. X., Shen N., Meurens F., Zhu J. 2020. Inter-relation analysis of signaling adaptors of porcine innate immune pathways. Molecular Immunology, 121:20-27 [IF19=3.641] DOI: 10.1016/j.molimm.2020.02.013.
  • Berri M., Hogan D., Saade G., Roche S., Velge P., Virlogeux-Payant I., Meurens F. 2020. IPEC-1 variable immune response to different serovars of Salmonella enterica subsp. enterica. Veterinary Immunology and Immunopathology, 220:109989 [IF19=1.713] DOI: 10.1016/j.vetimm.2019.109989.
  • Jiang S., Ao D., Ni J., Chen N., Meurens F., Zhu J. 2020. The signaling relations between three adaptors of porcine C-type lectin receptor pathway. Developmental & Comparative Immunology, 104:103555 [IF19=3.192] DOI: 10.1016/j.dci.2019.103555.
  • Khamisse E., Dunoyer C., Brown P., Gouilh M.A., Meurens F., Meyer G., Monchatre-Leroy E., Pavio N., Simon G., Lepoder S. 2020. SARS-CoV-2 and domestic animals : what relation? Animal, In press [IF19=2.400] DOI: 10.1016/j.ttbdis.2020.101494.
  • Li S., Yang J., Zhu Y., Ji X., Wang K., Jiang S., Luo J., Wang H., Zheng W., Chen N., Ye J., Meurens F., Zhu J. 2020. Chicken DNA Sensing cGAS-STING Signal Pathway Mediates Broad Spectrum Antiviral Functions. Vaccines, 8(3):369 [IF19=4.086] DOI: 10.3390/vaccines8030369.
  • Masset, N., Meurens, F., Marie, M., Lesage, P., Lehébel, A., Brisseau, N., Assié, S. 2020. Effectiveness of two intranasal vaccines for the control of bovine respiratory disease in newborn beef calves: A randomized non-inferiority multicentre field trial. The Veterinary Journal, 263:105532 [IF19=2.115] DOI: 10.1016/j.tvjl.2020.105532.
  • Saade G., Deblanc C., Bougon J., Marois-Crehan C., Fablet C., Auray G., Belloc C., Leblanc-Maridor M., Gagnon C.A., Zhu J., Gottschalk M., Summerfield A., Simon G., Bertho N., Meurens F. 2020. Coinfections and their molecular consequences in the porcine respiratory tract. Veterinary Research, 51(1):80 [IF19=3.357] DOI: 10.1186/s13567-020-00807-8.
  • Saade, G., Ménard, D., Hervet, C., Renson, P., Hue, E., Zhu, J., Dubreil, L., Paillot, R., Pronost, S., Bourry, O., Simon, G., Dupont, J., Bertho, N., and Meurens, F. 2020. Porcine Reproductive and Respiratory Syndrome Virus Interferes with Swine Influenza A Virus Infection of Epithelial Cells. Vaccines 8(3) [IF19=4.086] DOI: 10.3390/vaccines8030508.
  • Zheng, W., Zhou, R., Li, S., He, S., Luo, J., Zhu, M., Chen, N., Chen, H., Meurens, F., and Zhu, J. 2020. Porcine IFI16 Negatively Regulates cGAS Signaling Through the Restriction of DNA Binding and Stimulation. Frontiers in Immunology 11(1669) [IF19=5.085] DOI: 10.3389/fimmu.2020.01669.
  • Ao D., Xia P., Jiang S., Chen N., Meurens F., Zhu J. 2019. Comparative transcriptome analysis of TLR8 signaling cells revealed the porcine TLR8 specific differentially expressed genes. Developmental & Comparative Immunology, 98:129-136 [IF19=3.192] DOI: 10.1016/j.dci.2019.05.004.
  • Larcher T., Fablet C., Renson P., Ménard D., Hervet C., Saade G., Belloc C., Bourry O., Meurens F. 2019. Assessment of pulmonary responses in pigs challenged with PRRSV Lena strain shows better protection after immunization with field than vaccine strains. Veterinary Microbiology, 230:249-259 [IF19=3.030] DOI: 10.1016/j.vetmic.2019.01.022.
  • Levast B., Hogan D., van Kessel J., Strom S., Walker S., Zhu J., Meurens F., Gerdts V. 2019. Synthetic Cationic Peptide IDR-1002 and Human Cathelicidin LL37 Modulate the Cell Innate Response but Differentially Impact PRRSV Replication in vitro. Frontiers in Veterinary Science, 6:233 [IF19=2.245] DOI: 10.3389/fvets.2019.00233.
  • Almousa, A. A., Meurens, F., Krol, E. S., and Alcorn, J. 2018. Linoorbitides and enterolactone mitigate inflammation-induced oxidative stress and loss of intestinal epithelial barrier integrity. International Immunopharmacology 64:42-51. [IF19=3.943] DOI: 10.1016/j.intimp.2018.08.012.
  • Käser, T., Renois, F., Wilson, H. L., Cnudde, T., Gerdts, V., Dillon, J.-A. R., Jungersen, G., Agerholm, J. S., and Meurens, F. 2018. Contribution of the swine model in the study of human sexually transmitted infections. Infection, Genetics and Evolution In Press. [IF19=2.773] DOI: 10.1016/j.meegid.2017.11.022.
  • Kreuzer-Redmer S., Arends D., Schulte J. N., Karweina D., Korkuc P., Wöltje N., Hesse D., Pieper R., Gerdts V., Zentek J., Meurens F., Brockmann G. A. 2018. High dosage of zinc modulates T-cells in a time-dependent manner within porcine gut-associated lymphatic tissue. British Journal of Nutrition, 120(12):1349-1358 [IF19=3.334] DOI: 10.1017/S0007114518002908.
  • Maroilley, T., Berri, M., Lemonnier, G., Esquerré, D., Chevaleyre, C., Mélo, S., Meurens, F., Coville, J. L., Leplat, J. J., Rau, A., Bed’hom, B., Vincent-Naulleau, S., Mercat, M. J., Billon, Y., Lepage, P., Rogel-Gaillard, C., and Estellé, J. 2018. Immunome differences between porcine ileal and jejunal Peyer’s patches revealed by global transcriptome sequencing of gut-associated lymphoid tissues. Scientific Reports 8(1):9077 [IF19=3.998] DOI: 10.1038/s41598-018-27019-7.
  • Richard C. A., Hervet C., Ménard D., Gutsche I., Normand V., Meurens F., Eleouet J. F. 2018. First demonstration of the circulation of a pneumovirus in French pigs by detection of anti-swine orthopneumovirus nucleoprotein antibodies. Veterinary Research,  49(1):118  [IF19=3.357] DOI: 10.1186/s13567-018-0615-x.
  • Käser, T., Pasternak, J. A., Delgado-Ortega, M., Hamonic, G., Lai, K., Erickson, J., Walker, S., Dillon, J. R., Gerdts, V., and Meurens, F. 2017. Chlamydia suis and Chlamydia trachomatis induce multifunctional CD4 T cells in pigs. Vaccine 35(1):91-100 [IF19=3.143] DOI: 10.1016/j.vaccine.2016.11.050.
  • Moreau, E. and Meurens, F. 2017. Interleukins and large domestic animals, a bibliometric analysis. Heliyon 3(6):e00321. DOI: 10.1016/j.heliyon.2017.e00321.
  • Provost, C., Hamonic, G., Gagnon, C. A., and Meurens, F. 2017. Dual infections of CD163 expressing NPTr epithelial cells with influenza A virus and PRRSV. Veterinary Microbiology, 207(Supplement C):143-148 [IF19=3.030] DOI: 10.1016/j.vetmic.2017.06.012.
  • Chevaleyre, C., Riou, M., Brea, D., Vandebrouck, C., Barc, C., Pezant, J., Melo, S., Olivier, M., Delaunay, R., Boulesteix, O., Berthon, P., Rossignol, C., Burlaud Gaillard, J., Beck, F., Gauthier, F., Si-Tahar, M., Meurens, F., Berri, M., Caballero-Posadas, I., and Attuci, S. 2016. The Pig: A Relevant Model for Evaluating the Neutrophil Serine Protease Activities during Acute Pseudomonas aeruginosa Lung Infection. Plos One 11(12):e0168577 [IF19=2.740] DOI: 10.1371/journal.pone.0168577.
  • Deblanc, C., Delgado-Ortega, M., Gorin, S., Berri, M., Paboeuf, F., Berthon, P., Herrler, G., Meurens, F., and Simon, G. 2016. Mycoplasma hyopneumoniae does not affect the interferon-related anti-viral response but predisposes the pig to a higher inflammation following swine influenza virus infection. Journal of General Virology 97(10):2501-2515 [IF19=3.376] DOI: 10.1099/jgv.0.000573.
  • Hamonic, G., Pasternak, J. A., Käser, T., Meurens, F., and Wilson, H. L. 2016. Extended semen for artificial insemination in swine as a potential transmission mechanism for infectious Chlamydia suis. Theriogenology 86(4):949-956 [IF19=2.094] DOI: 10.1016/j.theriogenology.2016.03.018.
  • Käser, T., Pasternak, J. A., Hamonic, G., Rieder, M., Lai, K., Delgado-Ortega, M., Gerdts, V., and Meurens, F. 2016. Flow cytometry as an improved method for the titration of Chlamydiaceae and other intracellular bacteria. Cytometry Part A, 89(5):451-460 [IF19=3.124] DOI: 10.1002/cyto.a.22822.
  • Gerdts V., Wilson H. L., Meurens F., van Drunen Littel - van den Hurk S., Wilson D., Walker S., Wheler C., Townsend H., Potter A. A. 2015. Large Animal Models for Vaccine Development and Testing. ILAR Journal, 56(1):53-62. [IF19=2.250] DOI: 10.1093/ilar/ilv009.
  • Käser, T., Cnudde, T., Hamonic, G., Rieder, M., Pasternak, J. A., Lai, K., Tikoo, S. K., Wilson, H. L., Meurens, F. 2015. Porcine retinal cell line VIDO R1 and Chlamydia suis to modelize ocular chlamydiosis. Veterinary Immunology and Immunopathology 166(3-4):95-107 [IF19=1.713] DOI: 10.1016/j.vetimm.2015.06.003.

Voir aussi

Les publications de François Meurens dans ProdINRA