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Dernière mise à jour : Mai 2018

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Postdoctoral Resarch Post

A two years research assistant post is available at the UMR BioEpAR at Nantes, France.

The aims of the project are to conduct research on bovine tick borne babesiosis caused by Babesia divergens, in France and in Scotland. Specifically, evaluation of the genetic diversity of this parasite in order to study its population genetics will be undertaken. The project includes the development of microsatellite markers complemented with a Multi Locus Sequence Typing (MLST) approach, on genes subjected to or not subjected to selective pressure (house keeping genes and erythrocyte invasion related genes). The recent availability of Babesia divergens genome for two strains (one isolated from cattle and one isolated from human) will allow a bioinformatic search for these markers. The availability of a large collection of Babesia divergens isolates in the UMR BioEpAR will allow validation of the selected markers. The parasite genetic diversity will be studied at the multi-locus level for both countries (France and Scotland), at the herd level and within individual animals (co-infections). The project will provide information on the level of parasite population diversity and capacity for genetic exchange at these different levels.

 

Specifically, the job requires expert knowledge in molecular biology techniques, experience of working with large data sets and knowledge in population genetics. The successful candidate will also be expected to contribute to the formulation and submission of research publications and research proposals as well as manage and direct the project.

 

The available post would be based in Nantes, France under the supervision of Dr. Laurence Malandrin but would involve a collaborative work at the University of Glasgow (Prof Brian Shiels, Prof William Weir, Institute of Biodiversity, Animal Health and Comparative Medicine). Applications involving a detailed CV should be sent to laurence (dot) malandrin (at) oniris-nantes (dot) fr. The position is available from September/October 2014.