Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free:

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site:, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Google Analytics

Targeted advertising cookies


The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at or by post at:

24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal Institut Agro Rennes-Angers Angers University   IRHS




  • Howard N.P., Troggio M., Durel C.E., Muranty H., Denancé C., Bianco L., Tillman J., van de Weg E. Integration of Infinium and Axiom SNP array data in the outcrossing species Malus × domestica and causes for seemingly incompatible calls. BMC Genomics 22: 246
  • Malabarba J., Chevreau E., Dousset N., Veillet F., Moizan J., Vergne E. New strategies to overcome present CRISPR/Cas9 limitations in apple and pear: efficient dechimerization and base editing. International Journal of Molecular Sciences 22: 319


  • Bénéjam J., Ravon E., Gaucher M., Brisset M.N., Durel C.E., Perchepied L. Acibenzolar-S-methyl and resistance quantitative trait loci complement each other to control apple scab and fire blight. Plant Disease on line
  • Jung M., Roth M. , Aranzana M.J. , Auwerkerken A., Bink M., Denancé C., Dujak C., Durel C.-E., Font i Forcada C., Cantín C.M., Guerra W., Howard N., Lewandowski M., Ordidge M., Rymenants M., Sanin N., Studer B., Zurawicz E., Laurens F., Patocchi A., Muranty H. The apple REFPOP - a reference population for genomics-assisted breeding in apple. Horticulture Research 7:189
  • Roth M., Muranty H., Di Guardo M., Guerra W.,Patocchi A., Costa F. Genomic prediction of fruit texture and training population optimization towards the application of genomic selection in apple. Horticulture Research 7:148
  • Perrin A, Daccord N, Roquis D, Celton JM, Vergne E, Bucher E. Divergent DNA methylation signatures of juvenile seedlings, grafts and adult apple trees. Epigenomes, 04:04:00, 10.3390/epigenomes4010004
  • Muranty H., Denancé C., Feugey L., Crépin J.L., Barbier Y., Tartarini S., Ordidge M., Troggio M., Lateur M., Nybom H., Paprstein F., Laurens F., Durel C.E. Using whole-genome SNP data to reconstruct a large multi-generation pedigree in apple germplasm. BMC Plant Biology, 20:2, doi: 10.1186/s12870-019-2171-6


  • Petit-Houdenot, Y., Degrave, A.A., Meyer, M., Blaise, F., Ollivier, B., Marais, C.-L., Jauneau, A., Audran, C., Rivas, S., Veneault-Fourrey, C., Brun, H.H., Rouxel, T., Fudal, I., Balesdent, M.-H. A two genes – for – one gene interaction between Leptosphaeria maculans and Brassica napus. New Phytologist, 223: 397-411, doi: 10.1111/nph.15762
  • Charrier A., Vergne E., Joffrion C., Richer A., Dousset N., Chevreau E. An artificial miRNA as a new tool to silence and explore gene functions in apple. Transgenic Research, 28: 611-626, doi : 10.1007/s11248-019-0017-1
  • Nogué F., Vergne P., Chèvre A.M., Chauvin J.E., Bouchabké-Coussa O., Déjardin A., Chevreau E., Hibrand-Saint Oyant L., Mazier M., Barret P., Guiderdoni E., Sallaud C., Foucrier S., Devaux P., Rogowsky P.M. Crop plants with improved culture and quality traits for food, feed and other uses. Transgenic Research, 28: 65-73, doi : 10.1007/s11248-019-00135-4
  • Linsmith G, Rombauts S, Montanari S, Deng CH, Celton JM, Guerif P, Liu C, Lohaus R, Zurn JD, Cestaro A, Bassil NV, Bakker LV, Schijlen E, Gardiner SE, Lespinasse Y, Durel CE, Velasco R, Neale DB, Chagne D, Van de Peer Y, Troggio M, Bianco L. Pseudo-chromosome length genome assembly of a double haploid 'Bartlett' pear (Pyrus communis L.). GigaScience, 8:1-17, doi:10.1093/gigascience/giz138
  • Da Salveira Falavigna V, Malabarba J, PerieraSilveira  C, Buffon V, De Araujo Mariath JE, Pasquali G, Margis-Pinheiro M, Revers LF. Characterization of the nucellus-specific dehydrin MdoDHN11 demonstrates its involvment in the tolerance to water deficit. Plant Cell Reports, 38: 1099-1107, doi:10.1007/s00299-019-02428-8
  • Daudu, D., Kisiala, A., Werner Ribeiro, C., Mélin, C., Perrot, L., Clastre, M., Courdavault, V., Papon, N., Oudin, A., Courtois, M., Dugé de Bernonville, T., Gaucher, M., Degrave, A., Lanoue, A., Lanotte, P., Schouler, C., Brisset, M.N.,  Neil Emery, R.J., Pichon, O., Carpin, S., Giglioli-Guivarc'h, N., Crèche, J., Besseau, S., Glévarec, G. Setting-up a fast and reliable cytokinin biosensor based on a plant histidine kinase receptor expressed in Saccharomyces cerevisiae. Journal of Biotechnology, 289: 103–111,
  • Charrier A, Vergne E, Dousset N, Richer A, Petiteau A, Chevreau E. Efficient targeted mutagenesis in apple and first time edition of pear using the CRISPR-Cas9 system. Frontiers in Plant Science, 10:40, doi: 10.3389/fpls.2019.00040
  • Chevreau E., Dousset N., Joffrion C., Richer A., Charrier A., Vergne E. Agroinfiltration is a key factor to improve the efficiency of apple and pear transformation. Scientia Horticulturae, 251:150-154, doi:10.1016/j.scienta.2019.03.003
  • Le Mire, G., Siah, A., Marolleau, B., Gaucher, M., Maumené, C., Brostaux, Y., Massart, S., Brisset, M.N., Jijakli, M.H. Evaluation of λ-carrageenan, CpG-ODN, glycine betaine, Spirulina platensis and ergosterol as elicitors for the control of Zymoseptoria tritici in wheat. Phytopathology Journal, online on 8 Jan 2019,
  • Pelletier S, Gully K, Guillou LC, Ferrand, Aligon S, Pokotylo I, Perrin A, Vergne E, Fagard M, Rueland E, Grappin P, Bucher E, Renou JP, Aubourg S. The SCOOP12 peptide regulates defense response and root elongation in Arabidopsis thaliana. J Exp Bot, 70:1349-1365,
  • Gully K, Celton JM, Degrave A, Pelletier S, Brisset MN, Bucher E. Biotic Stress-Induced Priming and De-Priming of Transcriptional Memory in Arabidopsis and Apple. Epigenomes, 03:03, doi:10.3390/epigenomes3010003
  • Peace C., Bianco L., Troggio M., van de Weg E., Howard N.P., Cornille A., Durel C.E., Myles S., Migicovsky Z., Schaffer R., Costes E., Fazio G., Yamane H., van Nocker S., Gottschalk C., Costa F., Chagné D., Zhang X., Patocchi A., Gardiner S.E., Hardner C., Kumar S., Laurens F., Bucher E., Main D., Jung S., Vanderzande S. Apple whole genome sequences: recent advances and new prospects. Horticulture Research, 06:59, doi:10.1038/s41438-019-0141-7


  • Dall’Agata M., Pagliarani G., Padmarasu S., Troggio M., Bianco L., Dapena E., Miñarro M., Aubourg S., Lespinasse Y., Durel C.E., Tartarini S. Identification of candidate genes at the Dp-fl locus conferring resistance against the rosy apple aphid Dysaphis plantaginea. Tree Genetics & Genome, 14:1, 10.1007/s11295-018-1227-3
  • Daudu, D., Kisiala, A., Werner Ribeiro, C., Mélin, C., Perrot, L., Clastre, M., Courdavault, V., Papon, N., Oudin, A., Courtois, M., Dugé de Bernonville, T., Gaucher, M., Degrave, A., Lanoue, A., Lanotte, P., Schouler, C., Brisset, M.N., Neil Emery, R.J., Pichon, O., Carpin, S., Giglioli-Guivarc'h, N., Crèche, J., Besseau, S., Glévarec, G. Setting-up a fast and reliable cytokinin biosensor based on a plant histidine kinase receptor expressed in Saccharomyces cerevisiae. Journal of Biotechnology, 289: 103–111,
  • Lasserre-Zuber P., Caffier V., Stievenard R., Lemarquand A., Le Cam B., Durel C.E. Pyramiding quantitative resistance with a major resistance gene in apple: from ephemeral to enduring effectiveness in controlling apple scab. Plant Disease, 102:2220-2223,
  • Laurens F., Aranzana M.J., Arús P., Bassi D., Bink M., Bonany J., Caprera A., Corelli-Grapelli L., Costes E., Durel C.E., Mauroux J.B., Muranty H., Nazzicari N., Pascal T., Patocchi A., Peil A., Quilot-Turion B., Rossini L., Stella A., Troggio M., Velasco R., van de Weg E. An integrated approach for increasing breeding efficiency in apple and peach in Europe. Horticulture Research, 5:11, DOI 10.1038/s41438-018-0016-3
  • Le Mire, G., Siah, A., Brisset, M.N., Gaucher, M., Deleu, M., Haissam Jijakli, M.H. Surfactin protects wheat against Zymoseptoria tritici and activates both salicylic acid- and jasmonic acid-dependent defense responses. Agriculture, 8:11, doi:10.3390/agriculture8010011
  • Warneys R, Gaucher M, Robert P, Aligon S, Anton S, Aubourg S, Barthes N, Braud F, Cournol R, Gadenne C, Heintz C, Brisset MN, Degrave A. Acibenzolar-S-methyl reprograms apple transcriptome towards resistance to rosy aphid. Frontiers in Plant Science, 9: 1795,
  • van de Weg W.E., Di Guardo M., Jänsch M., Socquet-Juglard D., Costa F., Baumgartner I., Broggini G.A.L., Kellerhals M., Troggio M., Laurens F., Durel C.E., Patocchi A. Epistatic fire blight resistance QTL alleles in the apple cultivar 'Enterprise' and selection X-6398 discovered and characterized through pedigree-informed analysis. Molecular Breeding, 38:5, 10.1007/s11032-017-0755-0


  • Laloi G., Vergne E., Durel C.E., Le Cam B., Caffier V. Efficiency of pyramiding of three quantitative resistance loci to apple scab. Plant Pathology, 66:412-422, DOI: 10.1111/ppa.12581
  • Marolleau B, Gaucher M, Heintz C., Degrave A, Warneys R, Orain G., Lemarquand A, Brisset MN. When a plant resistance inducer leaves the lab for the field: Integrating ASM into routine apple protection practices. Frontiers in Plant Science, 8:1938, DOI: 10.3389/fpls.2017.01938
  • Pilet-Nayel M.L., Moury B., Caffier V., Montarry J., Kerlan M.C., Fournet S., Durel C.E., Delourme R. Quantitative resistance to plant pathogens in pyramiding strategies for durable crop protection. Frontiers in Plant Science, 8:1838, DOI: 10.3389/fpls.2017.01838
  • Urrestarazu J, Muranty H, Denancé C, Leforestier D, Ravon E, Guyader A, Guisnel R, Feugey L, Aubourg S, Celton JM, Daccord N, Dondini L, Gregori R, Lateur M, Houben P, Ordidge M, Paprstein F, Sedlak J, Nybom H, Garkava- Gustavson L, Troggio M, Bianco L, Velasco R, Poncet C, Theron A, Moriya S, Bink MCAM, Laurens F, Tartarini S, Durel CE. Genome-wide association mapping of flowering and ripening periods in apple. Frontiers in Plant Science, 8:1923, DOI: 10.3389/fpls.2017.01923
  • Moriya S., Kunihisa M., Okada K., Shimizu T., Honda C., Yamamoto T., Muranty H., Denancé C., Katayose Y., Iwata H., Abe  K., 2017, Allelic composition of MdMYB1 drives red skin color intensity in apple (Malus × domestica Borkh.) and its application to breeding. Euphytica, 213:78. doi: 10.1007/s10681-017-1864-x
  • DaccordN., Celton J.M., Linsmith G., Becker C., Choisne N., Schijlen E., van de Geest H., Bianco L., Micheletti D., Velasco R., Adele Di Pierro E., Gouzy J., Rees J.G., Guérif P., Muranty H., Durel C.E., Laurens F., Lespinasse Y., Gaillard S., Aubourg S., Quesneville H., Weigel D., van de Weg E., Troggio M.,  Bucher E., 2017, High-quality de novo assembly of the apple genome and methylome dynamics of early fruit development. Nature Genetics, 49:1099-1106, doi:10.1038/ng.3886


  • Plissonneau C, Daverdin G, Ollivier B, Blaise F, Degrave A, Fudal I, Rouxel T, Balesdent MH, 2016, A game of hide and seek between avirulence genes AvrLm4-7 and AvrLm3 in Leptosphaeria maculans. New Phytologist, 209:1613-1624
  • Bianco L., Cestaro A., Linsmith G., Muranty H., Denancé C., Théron A., Poncet C., Micheletti D., Kerschbamer E., Di Pierro E.A., Larger S., Pindo M., van de Weg W.E., Davassi A., Laurens F., Velasco R., Durel C.E., Troggio M. 2016. Development and validation of the Axiom®Apple480K SNP genotyping array. The Plant Journal, 86:62-74
  • Caffier V, Le Cam B, Al Rifaï M, Bellanger MN, Comby M, Denancé C, Didelot F, Expert P, Kerdraon T, Lemarquand A, Ravon E, Durel CE 2016. Slow erosion of a quantitative apple resistance to Venturia inaequalis based on an isolate-specific Quantitative Trait Locus. Infection, Genetics and Evolution, 44:541-548, DOI: 10.1016/j.meegid.2016.07.016
  • Laloi G., Vergne E., Durel C.E., Le Cam B., Caffier V. 2016. Efficiency of pyramiding of three quantitative resistance loci to apple scab. Plant Pathology, 66:412-422, DOI: 10.1111/ppa.12581
  • Lassois L., Denancé C., Ravon E., Guyader A., Guisnel R., Hibrand-Saint-Oyant L., Poncet C., Lasserre-Zuber P., Feugey L., Durel C.E. 2016. Genetic diversity, population structure, parentage analysis and construction of core collections in the French apple germplasm based on SSR markers. Plant Molecular Biology Reporter, 34:827-844
  • Leroy T, Caffier V, Celton JM, Anger N, Durel CE, Lemaire C, Le Cam B 2016. When virulence originates from non-agricultural hosts: evolutionary and epidemiological consequences of introgressions following secondary contacts in Venturia inaequalis. New Phytologist, 210: 1443–1452
  • Montanari S., Brewer L., Lamberts R., Velasco R., Malnoy M., Perchepied L., Guérif G., Durel C.E., Bus V.G.M., Gardiner S.E., Chagné D.  2016. Genome mapping of postzygotic hybrid necrosis in an interspecific pear population. Horticulture Research, 3, 15064
  • Montanari S., Perchepied L.,  Renault D., Frijters L., Velasco R., Horner M., Gardiner S.E., Chagné D., Bus V.G.M., Durel C.E., Malnoy M. 2016. A QTL detected in an interspecific pear population confers stable fire blight resistance across different environments and genetic backgrounds. Molecular Breeding, 36:47  DOI 10.1007/s11032-016-0473-z
  • Pagliarani G., Dapena E., Miñarro M., Denancé C., Lespinasse Y., Rat-Morris E., Troggio M., Durel C.E., Tartarini S. 2016. Fine mapping of the rosy apple aphid Dp-fl resistance  locus on Linkage Group 8 of the apple cultivar ‘Florina’. Tree Genetics & Genome, 12:56  DOI: 10.1007/s11295-016-1015-x
  • Poisson A.S., Berthelot P., Le Bras C., Grapin A., Vergne E., Chevreau E. 2016. A droplet-vitrification protocol enabled cryopreservation of doubled haploid explants of Malus x domestica Borkh. ‘Golden Delicious’. Scientia Horticulturae, 209, 187-191
  • Robert P., Braud F., Aligon S., Brisset M.N. 2016. DL-b-Aminobutyric acid application negatively affects reproduction and larval development of the rosy apple aphid, Dysaphis plantaginea, on apple. Entomologia Experimentalis er Applicata, 159: 46-53
  • Urrestarazu J., Denancé C., Ravon E., Guyader A., Guisnel R., Feugey L., Poncet C., Lateur M., Houben P., Ordidge M., Fernandez-Fernandez F., Evans K.M., Paprstein F., Sedlak J., Nybom H., Garkava-Gustavsson L., Miranda C., Gassmann J., Kellerhals M., Suprun I., Pikunova A.V., Krasova N.G., Torutaeva E., Dondini L., Tartarini S., Laurens F., Durel C.E. 2016. Analysis of the genetic diversity and structure across a wide range of germplasm reveals prominent gene flow in apple at the European level. BMC Plant Biology, 16:30  DOI: 10.1186/s12870-016-0818-0
  • Perchepied L., Guérif P., Ravon E., Denancé C., Laurens F., Robert P., Bouvier L., Lespinasse Y., Durel C.E. 2016. Polygenic inheritance of resistance to Cacopsylla pyri in a Pyrus communis x P. ussuriensis progeny is explained by three QTLs involving an epistatic interaction. Tree Genetics & Genome, 12:108
  • Di Pierro E.A., Gianfranceschi L., Di Guardo M., Koehorst - van Putten H.J.J., Kruisselbrink J.W., Longhi S., Troggio M., Bianco L., Muranty H., Pagliarani G., Tartarini S., Letschka T., Lozano Luis L., Garkava-Gustavsson L., Micheletti D., Bink M.C.A.M., Voorrips R.E., Aziz E., Velasco R., Laurens F., van de Weg  E. 2016. A high-density, multi-parental SNP genetic map on apple validates a new mapping approach for outcrossing species. Horticulture Research, 3, 16057


  • Bourget R., Chaumont L., Durel C.E., Sapoukhina N. 2015. Sustainable deployment of QTLs conferring quantitative resistance to crops: first lessons from a stochastic model. New Phytologist, 206:1163-1171
  • Caffier V., Patocchi A., Expert P., Bellanger M.N., Durel C.E., Hilber-Bodmer M., Broggini G.A.L., Groenwold R., Bus V.G.M. 2015. Virulence characterization of Venturia inaequalis reference isolates on the differential set of Malus hosts. Plant Disease, 99:370-375
  • Cova V., Lasserre-Zuber P., Piazza S., Cestaro A., Velasco R., Durel C.E., Malnoy M. 2015. High-resolution genetic and physical map of the Rvi1 (Vg) apple scab resistance locus. Molecular Breeding, 35:1-13
  • Degrave A., Siamer S., Boureau T., Barny M.A. 2015. The AvrE superfamily: Ancestral type III effectors involved in suppression of PAMP-triggered immunity. Molecular Plant Pathology, 16:899-905
  • Leforestier D., Ravon E., Muranty H., Cornillé A., Lemaire C., Giraud T., Durel C.E., Branca A. 2015. Genomic basis of the differences between cider and dessert apple varieties. Evolutionary Applications, 8: 650-661
  • Montanari S., Guérif P., Ravon E., Denancé C., Muranty H., Velasco R., Chagné D., Bus V.G.M., Robert P., Perchepied L., Durel C.E. 2015. Genetic mapping of Cacopsylla pyri resistance in an interspecific pear (Pyrus spp.) population. Tree Genetics & Genome, 11:74, DOI: 10.1007/s11295-015-0901-y
  • Lopez G., Pallas B., Martinez S., Lauri P.E., Regnard J.L., Durel C.E., Costes E. 2015. Genetic variation of morphological traits and transpiration in an apple core collection under well-watered conditions: towards the identification of morphotypes with high water use efficiency. PLOS One, 30;10(12):e014554
  • Muranty H., Troggio M., Ben Sadok I., Al Rifaï M, Auwerkerke A, Banchi E, Velasco R, Stevanato P,van de Weg  W.E., Di Guardo M., Kumar S., Laurens  F., Bink M.C.A.M. 2015. Accuracy and responses of genomic selection on key traits in apple breeding. Horticulture Research, 2, 15060
  • Perchepied L., Leforestier D., Ravon E., Guérif P., Denancé C., Tellier M., Terakami S., Yamamoto T., Chevalier M., Lespinasse Y., Durel C.E. 2015. Genetic mapping and pyramiding of two new pear scab resistance QTLs. Molecular Breeding, 35:197 DOI :10.1007/s11032-015-0391-5
  • Suprun I., Ushakova Y.V., Tokmakov S.V., Durel C.E., Denancé C., Ul'Yanovskaya E.V. 2015. Genetic diversity study of modern Russian apple (Malus domestica Borkh.) cultivars by the SSR loci analysis. Sel’Skokhozyaistvennaya Biologiya [Agricultural Biology] , 50:37-45


  • Muranty H., Jorge V., Bastien C., Lepoittevin C., Bouffier L., Sanchez L. 2014. Potential for Marker-Assisted Selection for forest tree breeding: lessons from 20 years of MAS in crops. Tree Genetics & Genome, 10:1494-1510
  • Dugé de Bernonville T., Marolleau B., Staub J., Gaucher M., Brisset M.N. 2014. Using molecular tools to decipher the complex world of plant resistance inducers: an apple case study. Journal of Agricultural and Food Chemistry, 62: 11403-11411
  • Celton JM, Kelner JJ, Martinez S, Bechti A, Khelifi Touhami A, James MJ, Durel CE, Laurens F, Costes E. 2014. Fruit self-thinning: a trait to consider for genetic improvement of apple tree. PLoS One, March; 9(3): e91016
  • Vergne E, Dugé de Bernonville T, Dupuis F,  Sourice S, Cournol R, Berthelot P,  Barny MA, Brisset MN, Chevreau E. 2014. Membrane targeted HrpNEa can modulate apple defense gene expression. Molecular Plant Microbe Interaction, 27: 125-135
  • Caffier V., Lasserre-Zuber P., Giraud M., Lascostes M., Stievenard R., Lemarquand A., van de Weg W.E., Expert P., Denancé C., Didelot F., Le Cam B., Durel C.E.. 2014. Erosion of quantitative host resistance in the apple x Venturia inaequalis pathosystem . Infection, Genetics and Evolution, 27: 481–489
  • Bink MCAM, Jansen J, Madduri M, Voorrips RE, Durel C-E, Kouassi AB,  Laurens F, Mathis F, Gessler C, Gobbin D, Rezzonico F, Patocchi A, Kellerhals M, Boudichevskaja K, Dunemann F, Peil A, Nowicka A, Lata B, Stankiewicz-Kosyl M, Jeziorek K, Pitera E, Soska A, Tomala K, Evans KM, Fernández-Fernández F, Guerra W, Korbin M, Keller S, Lewandowski M, Plocharski W, Rutkowski K, Zurawicz E, Costa F, Sansavinni S, Tartarini S, Komjanc M, Mott D, Antofie A, Lateur M, Rondia A, Gianfranceschi L, van de Weg WE. 2014. Bayesian QTL analyses using pedigreed families of an outcrossing species, with application to fruit firmness in apple. Theoretical & Applied Genetics, 127:1073-1090
  • Righetti L, Djennane S, Berthelot P, Cournol R, Wilmot N, Loridon K, Vergne E, Chevreau E. 2014. Elimination of the nptII marker gene in transgenic apple and pear with a chemically inducible R/Rs recombinase. Plant Cell Tissue and Organ Culture, 117: 335-348
  • Chagne D., Crowhurst R.N., Pindo M., Thrimawithana A., Deng C., Ireland H., Fiers M., Dzierzon H., Cestaro A., Fontana P., Bianco L., Lu A., Storey R., Knäbel M., Saeed M., Montanari S., Kim Y.K., Nicolini D., Larger S., Stefani E., Allan A.C., Bowen J., Harvey I., Johnston J., Malnoy M., Troggio M., Perchepied L., Sawyer G., Wiedow C., Won K., Viola R., Hellens R.P., Brewer L., Bus V.G.M., Schaffer R.J., Gardiner S.E., Velasco R.. 2014. The draft genome sequence of European pear (Pyrus communis L. ‘Bartlett’). PLOS One, April;9(4): e92644


  • Degrave A, Moreau M, Launay A, Barny MA, Brisset MN, Patrit O, Taconnat L, Vedel R, Fagard M. 2013. The bacterial effector DspA/E is toxic in Arabidopsis thaliana and is required for multiplication and survival of fire blight pathogen. Molecular Plant Pathology, 14:506-517
  • Gaucher M, Dugé de Bernonville T, Guyot S, Dat JF, Brisset MN. 2013. Same ammo, different weapons: enzymatic extracts from two apple genotypes with contrasted susceptibilities to fire blight (Erwinia amylovora) differentially convert phloridzin and phloretin in vitro. Plant Physiology & Biochemistry, 72:178-189
  • Gaucher M, Dugé de Bernonville T, Lohou D, Guyot S, Guillemette T, Brisset MN, Dat JF. 2013. Histolocalisation and physicol-chemical characterization of dihydrochalcones: insight into the role of apple major flavonoids. Phytochemistry, 90:78-89
  • Huard-Chauveau C, Perchepied L, Debieu M, Rivas S, Kroj T, Kars I, Bergelson J, Roux F, Roby D (2013) An Atypical Kinase under Balancing Selection Confers Broad-Spectrum Disease Resistance in Arabidopsis. PLoS Genet, 9(9): e1003766
  • Lê Van A, Caffier V, Lasserre-Zuber P, Chauveau A, Brunel D, Le Cam B, Durel CE. 2013. Differential selection pressures exerted by host resistance quantitative trait loci on a pathogen population: a case study in an apple x Venturia inaequalis pathosystem. New Phytologist, 197:899-908
  • Montanari S, Saeed M, Knäbel M, Kim YK, Troggio M, Malnoy M, Velasco R, Fontana P, Won KH, Durel CE, Perchepied L, Schaffer R, Wiedow C, Bus V, Brewer L, Gardiner SE, Crowhurst RN, Chagné D 2013 Identification of Pyrus single nucleotide polymorphisms (SNPs) and evaluation for genetic mapping in European pear and interspecific Pyrus hybrids. PlosOne, Oct;8(10): e77022
  • Siamer S., Gaubert S., Boureau T., Brisset MN, Barny MA. 2013. Mutational analysis of a predicted double b-propeller domain of the DspA/E effector of Erwinia amylovora. FEMS Microbiology Letters, 342:54-61


  • Bouvier L., Bourcy M., Boulay M., Tellier M., Guérif P., Denancé C., Durel C.E., Lespinasse Y. 2012. A new pear scab resistance gene Rvp1 from the European pear cultivar ‘Navara’ maps in a genomic region syntenic to an apple scab resistance gene cluster on linkage group 2. Tree Genetics and Genome, 8:53-60
  • Caffier V., Le Cam B., Expert P., Tellier M., Devaux M, Giraud M., Chevalier M., 2012. A new scab-like disease on apple caused by the formerly saprotrophic fungus Venturia asperata.Plant Pathology, 61:915-924
  • Degrave A, Moreau M, Vedel R, Taconnat L, Patrit O, Renou JP, Barny M,A, and Fagard M. 2012. EDS1 contributes to non-host resistance of A. thaliana against E. amylovora. Molecular Plant Microbe Interaction 25:421-430
  • Dugé De Bernonville T., Gaucher M., Flors V., Gaillard S., Paulin J-P., Dat J.F., Brisset M-N. 2012. T3SS dependent differential modulations of the jasmonic acid pathway in susceptible and resistant genotypes of Malus spp. challenged with Erwinia amylovora. Plant Science, 188-189:1-9
  • Freiman A., Shlizerman L., Golubowicz S., Yabloviz Z., Korchinsky R., Cohen Y., Samach A., Chevreau E., Le Roux P.M, Patocchi A., Flaishman M.A. 2012. Development of a transgenic early flowering pear (Pyrus communis L.) genotype by RNAi silencing of PcTFL1-1 and PcTFL1-2. Planta, 235:1239-1251
  • Le Roux P-M., Christen D., Duffy B., Tartarini S., Dondini L., Yamamoto T., Nishitani C., Terakami S., Lespinasse Y., Kellerhals M., Patocchi A. 2012. Redefinition of the map position and validation of a major quantitaive trait locus for fire blight resistance of the pear cultivar 'Harrow Sweet' (Pyrus communis L.). Plant Breeding, 131:656-664
  • Lê Van A., Gladieux P., Lemaire C., Cornille A., Giraud T., Durel C.E., Caffier V., Le Cam B. 2012. Evolution of pathogenicity traits in the apple scab fungal pathogen in response to the domestication of its host. Evolutionnary Applications, 5: 694-704


  • Boureau T., Perino C., Gaubert S., Siamer S., Patrit O., Degrave A., Fagard M., Chevreau E., Barny M-A.  The HrpN effector of the plant pathogen Erwinia amylovora participates to Type III translocation and is required to trigger callose deposition during disease. Molecular Plant Microbe Interaction, 24: 577-584.
  • Bus V.G.M, Rikkerink E.H.A, Caffier V.,Durel C.E, Plummer K.M. Revision of the nomenclature of the differential host-pathogen interactions of Venturia inaequalis and Malus.2011. Annu. Rev. Phytopathol. 2011. 49:19.1–19.2Chevreau E., Dupuis F., Taglioni J.P., Sourice S., Cournol R., Deswartes C., Bersegeay A., Descombin J., Siegwart M., Loridon  K. 2011. Effect of ectopic expression of the eutypine detoxifying gene Vr-ERE in transgenic apple plants. Plant Cell Tissue and Organ Culture, 2011 106 : 161-168.
  • Djennane S., Cesbron C., Sourice S., Cournol R., Dupuis F., Eychenne M., Loridon K.,  Chevreau E., 2011. Iron homeostasis and fire blight susceptibility in transgenic pear plants overexpressing a pea ferritin gene. Plant Science, 2011 180: 694–701.
  • Dugé de Bernonville T, Gaucher M, Guyot S, Durel CE, Dat JF, Brisset MN 2011. The constitutive phenolic composition of two Malus x domestica genotypes is not responsible for their contrasted susceptibilities to fire blight.  Environmental and Experimental Botany, 2011 74:65-73
  • Evans K.M.,  Patocchi A., Rezzonico F., Mathis F., Durel C.E.,  Fernández-Fernández F.,  Boudichevskaia A., Dunemann F.,  Stankiewicz-Kosyl M.,  Gianfranceschi L., Komjanc M., Lateur M., Madduri M., Noordijk Y.,  van de Weg W.E., 2011 Genotyping of pedigreed apple breeding material with a genome covering set of SSRs:  Trueness to type of cultivars and their parentages. Molecular Breeding,2011 28:535-547
  • Lê Van, A., Durel, C-E., Le Cam, B. Caffier, V. 2011. The threat of wild habitat to scab resistant apple cultivars. Plant Pathology 4:621-630
  • Parravicini G., Gessler C., Denancé C., Lasserre P., Vergne É., Brisset M-N., Patocchi A., Durel C.E., Broggini G. A. L. 2011. Identification of Ser/Thr kinase and NBS-LRR genes in the fire blight resistance QTL of apple cultivar ‘Evereste’. Molecular Plant Pathology 5:493-505


  • Caffier V., Didelot F., Pumo B., Causeur D., Durel C.E., Parisi L. Aggressiveness of eight Venturia inaequalis isolates virulent or avirulent to the major resistance gene Rvi6 on a non-Rvi6 apple cultivar. Plant Pathology 59: 1072–1080
  • Darrasse A.,  Darsonval A., Boureau T., Brisset M.N., Durand K., Jacques M.A. 2010. Transmission of plant-pathogenic bacteria by nonhost seeds without induction of an associated defense reaction at emergence. Applied and Environmental Microbiology 76: 6787-6796
  • Duge de Bernonville T., Guyot S., Paulin J.P., Gaucher M., Loufrani L., Henrion D., Derbre S., Guilet D., Richomme P., Dat J., Brisset M.N., 2010. Dihydrochalcones: Implication in resistance to oxidative stress and bioactivities against advanced glycation end-product and vasoconstriction. Phytochemistry 71, 443-452.
  • Velasco R, Zharkikh A, Affourtit J, Dhingra A, Cestaro A, Kalyanaraman A, Fontana P, Bhatnagar S, Troggio M, Pruss D, Salvi S, Pindo M, Baldi P, Cavaiuolo M, Coppola G, Costa F, Cova V, Dal Ri A, Goremykin V, Komjanc M, Longhi S, Magnago P, Malacarne G, Malnoy M, Micheletti D, Moretto M, Perazzolli M, Si Ammour A, Vezzulli S, Zini E, Eldredge G, Fitzgerald LM, Gutin N, Lanchbury J, Macalma T, Mitchell JT, Reid J, Wardell B, Chen Z, Desany B, Niazi F, Palmer M, Koepke T, Jiwan D, Schaeffer S, Krishnan V, Wu C, Chu VT, King ST, Vick J, Tao Q, Mraz A, Stormo A, Stormo K, Bogden R, Ederle D, Stella A, Vecchietti A, Kater MM, Masiero S, Lasserre P, Lespinasse Y, Allan AC, Bus V, Chagné D, Crowhurst RN, Gleave AP, Lavezzo E, Fawcett JA, Proost S, Rouzé P, Sterck L, Toppo S, Lazzari B, Hellens RP, Durel CE, Gutin A, Bumgarner RE, Gardiner SE, Skolnick M, Egholm M, Van de Peer Y, Salamini F,8, Viola R. The genome of the domesticated apple (Malus x domestica). Nature Genetics 42, 833-841.


  • Dispositif pour déterminer ou étudier l’état de stimulation des défenses naturelles de plantes ou parties de plantes appartenant à la famille des Rosaceae. Duge de Bernonville T., Brisset M.N., 2010. Demande de brevet d’invention DI-RV-08-0050 - W 637 - 5894 K. Dépôt auprès de l’INPI sous le numéro 10 55042 le 24 juin 2010. Référence INRA UCPI : DI-RV-0860050.


  • Darsonval A., Darrasse A., Durand C., Bureau S., Cesbron S., Jacques M.A., 2009. Adhesion and fitness in the bean phyllosphere and transmission to seed of Xanthomonas fuscans subsp fuscans. Molecular Plant- Microbe Interactions 22, 747-757.
  • Durel C.E., Denancé C.D., Brisset M.N.,  2009. Two distinct major QTL for resistance to fire blight co-localise on linkage group 12 in apple genotypes Evereste and Malus floribunda clone 821. Genome, 52, 139-147.
  • Kouassi A.B., Durel C.E., Costa F., Tartarini S., van de Weg E., Evans K., Fernandez-Fernandez F., Govan C., Boudichevskaja A., Dunemann F., Antofie A., Lateur M., Stankiewicz-Kosyl M., Soska A., Tomala K., Lewandowski M., Rutkovski K., Zurawicz E., Guerra W., Laurens F., 2009. Estimation of genetic parameters and prediction of breeding values for apple fruit-quality traits using pedigreed plant material in Europe. Tree Genetics & Genomes, 5, 659-672.
  • Patocchi A., Fernández-Fernández F., Evans K., Gobbin D., Rezzonico F., Boudichevskaia A., Dunemann F., Stankiewicz-Kosyl M., Mathis-Jeanneteau F., Durel C.E., Gianfranceschi L., Costa F., Toller C., Cova V., Mott D., Komjanc M., Barbaro E., Kodde L., Rikkerink E., Gessler C., van de Weg W.E., 2009. Development and test of 21 multiplex 1 PCRs composed of SSRs spanning most of the apple genome. Tree Genetics and Genome 5, 211-223.
  • Sapoukhina N. Durel C.E., Le Cam B. 2009. Spatial deployment of gene-for-gene resistance governs evolution and spread of pathogen populations. Theoretical Ecology, 2, 229-238
  • Segura V., Durel C.E., Costes E., 2009. Dissecting apple tree architecture into genetic, ontogenetic and environmental effects. II: QTL mapping. Tree Genetics and Genome 5, 165-179.

Ouvrages scientifiques ou chapitres

  • Yamamoto T., Chevreau E., 2009.  Pear genomics. In : K. M. Folta and S. E. Gardiner (Eds.), “Genetics and Genomics of  Rosaceae” (part I, chap. 8).  Springer, New York, pp 163-186.


  • Bus V.G.M., Chagné D., Bassett H.C.M., Bowatte D., Calenge F., Celton J.M., Durel C.E., Malone M.T., Patocchi A., Ranatunga AC., Rikkerink E.H.A., Tustin DS., Zhou J., Gardiner SE., 2008. Genome mapping of three major resistance genes to woolly apple aphid (Eriosoma lanigerum Hausm.). Tree Genetics and Genomes, 4, 233-236
  • Chevalier M., Parisi L., Gueye B., Campion C., Simoneau P., Poupard P., 2008. Specific activation of PR-10 pathogenesis-related gene in apple by an incompatible race of Venturia inaequalis. Biologia Plantarum, 52, 718-722
  • Degrave A., Fagard M., Perino C., Brisset M.N., Gaubert S., Laroche S., Patrit O., Barny M.A., 2008. Erwinia amylovora type three-secreted proteins trigger cell death and defense responses in Arabidopsis thaliana. Molecular Plant- Microbe Interactions 21, 1094-1105.
  • N’Diaye A., van de Weg E.W., Kodde L.P., Koller B., Dunemann F., Thiermann M., Tartarini S., Gennari F.,  Durel C.E., 2008 Construction of an integrated consensus map of the apple genome  based on four mapping populations. Tree Genetics and Genome 4, 727-743.
  • Pontais I., Treutter D., Paulin J.P., Brisset M.N., 2008. Erwinia amylovora modifies phenolic profiles of susceptible and resistant apple through its type III secretion system. Physiologia Plantarum 132, 262-271.
  • Soufflet-Freslon V., Gianfranceschi L., Patocchi A., Durel C.E., 2008. Inheritance studies on apple scab resistance identify Rvi14, a new major gene, and confirm two broad-spectrum QTL. Genome 51, 657-667.


  • Antofie A., Lateur M., Oger R., Patocchi A., Durel C.E., van de Weg W.E., 2007. A new versatile database created for geneticists and breeders to link molecular and phenotypic data in perennial crops : the AppleBreed DataBase. Bioinformatics, 23 (7), 882-891
  • Khan M.A., Durel C.E., Duffy B., Drouet D., Kellerhals M., Gessler C., Patocchi A., 2007. Development of molecular markers linked to the ‘Fiesta’ linkage group 7 major QTL for fire blight resistance and their application for marker-assisted selection. Genome, 50, 568-577.
  • Segura V., Denancé C., Durel C.E., Costes E., 2007. Wide range QTL analysis for complex architectural traits in a 1-year-old apple progeny. Genome, 50, 159-171.


  • Boureau T., El Maarouf-Bouteau H., Garnier A., Brisset M.N., Perino C., Pucheu I., Barny M.A., 2006. DspA/E, a type III effector essential for Erwinia amylovora pathogenicity and growth in planta, induces cell death in host apple and nonhost tobacco plants. Molecular Plant-Microbe Interactions 19, 16-24.
  • Calenge F., Durel C.-E., 2006.  Both stable and unstable QTLs for resistance to powdery mildew are detected in apple after four years of field assessments. Molecular Breeding, 17, 329-339.
  • Cesbron S., Paulin J.P., Tharaud M., Barny M.A., Brisset M.N., 2006. The alternative σ factor HrpL negatively modulates the flagellar system in the phytopathogenic bacterium Erwinia amylovora under hrp-inducing conditions. FEMS Microbiology Letters 257, 221-227.
  • Faize M., Brisset M.N., Perino C., Vian B., Barny M.A., Paulin J.P., Tharaud M., 2006. Protection of apple against fire blight induced by an hrpL mutant of Erwinia amylovora. Biologia Plantarum 50, 667-674.
  • Silferberg-Dilworth E., Matasci C.L., van de Weg W.E., van Kaauwen M.P.W., Walser M., Kodde L.P., Soglio V., Gianfranceschi L., Durel C.E., Costa F., Yamamoto T., Koller B., Gessler C., Patocchi A., 2006. Microsatellite markers spanning the apple (Malus x domestica Borkh.) genome. Tree Genetics & Genomes, 2, 202-224.