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42, rue Georges Morel
BP 60057
49071 Beaucouzé
Building: IRHS-Bâtiment A
Office: A1-71
Phone : +33 2 4122 5671
Fax : +33 2 4122 5755
email : laurine.lambelin@inrae.fr

I'm a PhD student studying rose resistance to black spot disease.

My background

After two years of Agro-véto preparatory classes, I joined Agrocampus Ouest (Rennes center) where I followed the "Ingénieur Agronome" course for three years. In Master 1, I specialized in plant genetics, a subject that has always fascinated me. During my Master 2 internship, I studied the genetic basis of flowering in cherry trees. Then I chose to pursue a thesis, and the theme of flowers hasn't left me: my thesis subject is the interaction between the rose and a pathogenic fungus!

My skills

Quantitative genetics, Population genetics, Statistics and bioinformatics (R), Plant biology, Host-pathogen interactions, English

My thesis topic

Identification of candidate genes in the quantitative resistance of rose to black spot disease caused by the fungus Diplocarpon rosae.

Background and objectives of my thesis

Garden roses (genus Rosa) are susceptible to a leaf disease, black spot, caused by the fungus Diplocarpon rosae. Studying the genetic resistance of roses to black spot is essential in order to understand the mechanisms involved and to be able to select varieties that will not be affected by this disease. Two QTL for resistance to black spot were recently detected in Rosa wichurana (Lopez Arias et al., 2020).

The main objective of my thesis is to characterize the interaction of each of these QTL and their combination with D. rosae, at the histological and molecular levels.

My main research questions are as follows

At what stage(s) of infection do the QTLs act? What biological processes are involved?
What genomic variants have been identified within the confidence intervals of these QTLs?
What are the candidate genes underlying the QTLs, and the functions associated with the QTLs? 
Thus, I will study the offspring of the cross between resistant R. wichurana and a susceptible rose. I will use microscopy, RNA-seq and sequence comparison approaches between resistant and susceptible genotypes.

Curriculum Vitae