Know more

About cookies

What is a "cookie"?

A "cookie" is a piece of information, usually small and identified by a name, which may be sent to your browser by a website you are visiting. Your web browser will store it for a period of time, and send it back to the web server each time you log on again.

Different types of cookies are placed on the sites:

  • Cookies strictly necessary for the proper functioning of the site
  • Cookies deposited by third party sites to improve the interactivity of the site, to collect statistics

Learn more about cookies and how they work

The different types of cookies used on this site

Cookies strictly necessary for the site to function

These cookies allow the main services of the site to function optimally. You can technically block them using your browser settings but your experience on the site may be degraded.

Furthermore, you have the possibility of opposing the use of audience measurement tracers strictly necessary for the functioning and current administration of the website in the cookie management window accessible via the link located in the footer of the site.

Technical cookies

Name of the cookie


Shelf life

CAS and PHP session cookies

Login credentials, session security



Saving your cookie consent choices

12 months

Audience measurement cookies (AT Internet)

Name of the cookie


Shelf life


Trace the visitor's route in order to establish visit statistics.

13 months


Store the anonymous ID of the visitor who starts the first time he visits the site

13 months


Identify the numbers (unique identifiers of a site) seen by the visitor and store the visitor's identifiers.

13 months

About the AT Internet audience measurement tool :

AT Internet's audience measurement tool Analytics is deployed on this site in order to obtain information on visitors' navigation and to improve its use.

The French data protection authority (CNIL) has granted an exemption to AT Internet's Web Analytics cookie. This tool is thus exempt from the collection of the Internet user's consent with regard to the deposit of analytics cookies. However, you can refuse the deposit of these cookies via the cookie management panel.

Good to know:

  • The data collected are not cross-checked with other processing operations
  • The deposited cookie is only used to produce anonymous statistics
  • The cookie does not allow the user's navigation on other sites to be tracked.

Third party cookies to improve the interactivity of the site

This site relies on certain services provided by third parties which allow :

  • to offer interactive content;
  • improve usability and facilitate the sharing of content on social networks;
  • view videos and animated presentations directly on our website;
  • protect form entries from robots;
  • monitor the performance of the site.

These third parties will collect and use your browsing data for their own purposes.

How to accept or reject cookies

When you start browsing an eZpublish site, the appearance of the "cookies" banner allows you to accept or refuse all the cookies we use. This banner will be displayed as long as you have not made a choice, even if you are browsing on another page of the site.

You can change your choices at any time by clicking on the "Cookie Management" link.

You can manage these cookies in your browser. Here are the procedures to follow: Firefox; Chrome; Explorer; Safari; Opera

For more information about the cookies we use, you can contact INRAE's Data Protection Officer by email at or by post at :


24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

Menu Logo Principal Institut Agro Rennes-Angers Angers University   IRHS


Publications & COV


  • Bouargalne Y, Guilbaud F, Macherel D, Delalande O, Deleu C, Le Cahérec F (2023) Brassica Napus Drought-Induced 22-Kilodalton Protein (BnD22) Acts Simultaneously as a Cysteine Protease Inhibitor and Chlorophyll-Binding Protein. Plant Cell and Physiology 64(5): 536-548.
  • Broussard L, Abadie C, Lalande J, Limami AM, Lothier J, Tcherkez G (2023) Phloem Sap Composition: What Have We Learnt from Metabolomics ? International Journal of Molecular Sciences 24(8): 6917.
  • Domergue J-B, Bocca C, De Paepe R, Lenaers G, Limami AM, Tcherkez G (2023) Mitochondrial complex I disruption causes broad reorchestration of plant lipidome including chloroplast lipids. International Journal of Molecular Sciences 24(1): 453.
  • Holloway-Phillips M, Cernusak LA, Nelson DB, Lehmann MM, Tcherkez G, Kahmen A (2023) Covariation between oxygen and hydrogen stable isotopes declines along the path from xylem water to wood cellulose across an aridity gradient. New Phytologist doi: 10.1111/nph.19248.
  • Limami AM, Cukier C, Hirel B (2023) 15N-labelling of leaves combined with GC-MS analysis as a tool for monitoring the dynamics of nitrogen incorporation into amino acids. In Methods in Molecular Biology, Humana New York, NY, USA, vol. 2642, pp 151–161. 
  • Limami AM, Hirel B (2023) Editorial: The role of nitrate in plant response to biotic and abiotic stress. Frontiers in Plant Sciences 14: 1240256.
  • Malécange M, Sergheraert R, Teulat B, Mounier E, Lothier J, Sakr S (2023) Biostimulant Properties of Protein Hydrolysates: Recent Advances and Future Challenges. International Journal of Molecular Sciences 24(11): 9714.
  • Milić D, Živanović B, Samardžić J, Nikolić N, Cukier C, Limami AM, Vidović M (2023) Carbon and Nitrogen Allocation between the Sink and Source Leaf Tissue in Response to the Excess Excitation Energy Conditions. International Journal of Molecular Sciences 24(3): 2269.
  • Porcher A, Guérin V, Macherel D, Lebrec A, Satour P, Lothier J, Vian A (2023) High Expression of ALTERNATIVE OXIDASE 2 in Latent Axillary Buds Suggests Its Key Role in Quiescence Maintenance in Rosebush. Plant Cell and Physiology 64(21): 165-175.
  • Renou S, Grand M, Daux V, Tcherkez G, Akoka S, Remaud G (2023) NMR-Based Method for Intramolecular 13C Distribution at Natural Abundance Adapted to Small Amounts of Glucose. Analytical Chemistry 95(28): 10540-10549.
  • Sun YR, Ma WT, Xu YN, Wang X, Li L, Tcherkez G, Gong XY (2023) Short- and long-term responses of leaf day respiration to elevated atmospheric CO2. Plant Physiology 191(4): 2204-2217.
  • Tarkowski ŁP, Signorelli S, Considine MJ, Montrichard F (2023) Integration of reactive oxygen species and nutrient signalling to shape root system architecture. Plant Cell & Environment 46(2): 379-390.
  • Tcherkez G, Holloway-Phillips M, Lothier J, Limami A, Ball MC (2023) Revisiting yield in terms of phloem transport to grains suggests phloem sap movement might be homeostatic. Plant Cell & Environment 46(9): 2667-2679.
  • Tercé-Laforgue T, Lothier J, Limami AM, Rouster J, Lea PJ, Hirel B (2023) The Key Role of Glutamate Dehydrogenase 2 (GDH2) in the Control of Kernel Production in Maize (Zea mays L.). Plants 12(14): 2612.


  • Abadie C, Lalande J, Tcherkez G (2022) Exact mass GC-MS analysis: Protocol, database, advantages and application to plant metabolic profiling. Plant Cell & Environment 45(10):3171-3183.
  • Barrit T, Campion C, Aligon S, Bourbeillon J, Rousseau D, Planchet E, Teulat B (2022) A new in vitro monitoring system reveals a specific influence of Arabidopsis nitrogen nutrition on its susceptibility to Alternaria brassicicola at the seedling stage. Plant Methods 18(1): 131.
  • Barrit T, Porcher A, Cukier C, Satour P, Guillemette T, Limami AM, Teulat B, Campion C, Planchet E (2022) Nitrogen nutrition modifies the susceptibility of Arabidopsis thaliana to the necrotrophic fungus, Alternaria brassicicola. Physiologia Plantarum 174(1): e13621.
  • Bathelier C, Tcherkez G (2022) Experimental evidence for extra proton exchange in ribulose 1,5-bisphosphate carboxylase/oxygenase catalysis. Communicative & Integrative Biology 15(1): 68-74.
  • Boeglin L, Morère Le-Paven MC, Clochard T, Fustec J, Limami AM (2022) Pisum sativum response to nitrate as affeted by Rhizobium leguminosarum-derived signals. Plants 11(15): 1966.
  • Bréard D, Barrit T, Le Corff J, Aligon S, Sochard D, Planchet E, Teulat B, Campion C, Guilet B (2022) Development of a quantification method for routine analysis of glucosinolates and camalexin in Brassicaceous small-sized samples by simultaneous extraction prior to liquid chromatography determination. Journal of Chromatography B 1205: 123348.
  • Domergue J-B, Abadie C, Lalande J, Deswarte JC, Ober E, Laurent V, Zimmerli C, Lerebour P, Duchalais L, Bédard C, Derory J, Moittie T, Lamothe-Sibold M, Beauchêne K, Limami AM, Tcherkez G (2022) Grain carbon isotope composition is a marker for allocation and harvest index in wheat. Plant Cell & Environment 45: 2145–2157.
  • Domergue J-B, Lalande J, Abadie C, Tcherkez G (2022) Compound-specific 14N/15N analysis of amino acid trimyethylsylated derivatives from plant seed proteins. International Journal of Molecular Sciences 23(9): 4893.
  • Domergue J-B, Lalande J, Beucher D, Satour P, Abadie C, Limami AM, Tcherkez G (2022) Experimental evidence for seed metabolic allometry in barrel medic (Medicago truncatula Gaertn.). International Journal of Molecular Sciences 23(15): 8484.
  • Fan Y, Asao S, Furbank RT, von Caemmerer S, Day DA, Tcherkez G, Sage TL, Sage RF, Atkin OK (2022) The crucial roles of mitochondria in supporting C4 photosynthesis. New Phytologist 233(3): 1083-1096.
  • Fouet MPA, Singer D, Coynel A, Héliot S, Howa H, Lalande J, Mouret A, Schweizer M, Tcherkez G, Jorissen FJ (2022) Foraminiferal distribution in two estuarine intertidal mudflats of the french atlantic coast: Testing the marine influence index. Water 14(4): 645.
  • Ghaleb W, Barre P, Teulat B, Ahmed L, Escobar-Gutiérrez AJ (2022) Divergent selection for seed ability to germinate at extreme temperatures in perennial ryegrass (Lolium perenne L.). Frontiers in Plant Sciences 12: 794488.
  • Gong XY, Ma WT, Yu YZ, Fang K, Yang Y, Tcherkez G, Adams MA (2022) Overestimated gains in water-use efficiency by global forests. Global Change Biology 28(16): 4923-4934.
  • Guillou MC, Vergne E, Aligon S, Pelletier S, Simonneau F, Rolland A, Chabout S, Mouille G, Gully K, Grappin P, Montrichard F, Aubourg S, Renou JP (2022) SCOOP12 peptide acts on ROS homeostasis to modulate cell division and elongation in Arabidopsis primary roots. Journal of Experimental Botany 11(24): 3554.
  • Holloway-Phillips M, Baan J, Nelson DB, Lehmann MM, Tcherkez G, Kahmen A (2022) Species variation in the hydrogen isotope composition of leaf cellulose is mostly driven by isotopic variation in leaf sucrose. Plant Cell & Environment 45(9): 2636-2651.
  • Limami A. Hirel B, Lothier J (2022) Does Potassium (K+) contribute to High-Nitrate (NO3-) weakening of a plant’s defense system against necrotrophic fungi? International Journal of Molecular Sciences 23: 1563.
  • Malécange M, Pérez-Garcia MD, Citerne S, Sergheraert R, Lalande J, Teulat B, Mounier E, Sakr S, Lothier J (2022) Leafamine ®, a free amino acid-rich biostimulant, promotes growth performance of deficit-irrigated lettuce. International Journal of Molecular Sciences 23(13): 7338.
  • Zang L, Tarkowski LP, Morère-Le Paven MC, Zivy M, Balliau T, Clochard T, Bahut M, Balzergue S, Pelletier S, Landès C, Limami AM, Montrichard F (2022) The nitrate transporter MtNPF6.8 is a master sensor of nitrate signal in the primary root tip of Medicago truncatula. Frontiers in Plant Sciences 13: 832246.


  • Abadie C, Lalande J, Limami AM, Tcherkez G (2021) Non-targeted 13C metabolite analysis demonstrates broad re-orchestration of leaf metabolism when gas exchange conditions vary. Plant Cell & Environment  44: 445-457.
  • Abadie C, Tcherkez G (2021) 13C Isotope Labelling to Follow the Flux of Photorespiratory Intermediates. Plants 10: 427.
  • Amiour N, Décousset L, Rouster J, Quenard N, Buet C, Dubreuil P, Quilleré I, Brulé L, Cukier C, Dinant S, Sallaud C, Dubois F, Limami AM, Lea PJ, Hirel B (2021) Impacts of environmental conditions, and allelic variation of cytosolic glutamine synthetase on maize hybrid kernel production. Communications Biology 4: 1095.
  • Cui J, Davanture M, Lamade E, Zivy M, Tcherkez G (2021) Plant low-K responses are partly due to Ca prevalence and the low-K biomarker putrescine does not protect from Ca side effects but acts as a metabolic regulator. Plant Cell & Environment 44: 1565-1579.
  • Cui J, Nieves-Cordones M, Rubio F, Tcherkez G (2021) Involvement of salicylic acid in the response to potassium deficiency revealed by metabolomics. Plant Physiology and Biochemistry 163: 201-204.
  • Cui J, Peuke AD, Limami AM, Tcherkez G (2021) Why is phloem sap kept low? Plant Cell & Environment 44: 2838-2843.
  • Cui J, Tcherkez G (2021) Potassium dependency of enzymes in plant primary metabolism. Plant Physiology and Biochemistry 166: 522-530.
  • Duminil P, Davanture M, Oury C, Boex-Fontvieille E, Tcherkez G, Zivy M, Hodges M, Glab N (2021) Arabidopsis thaliana 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 2 activity requires serine 82 phosphorylation. Plant Journal 107(5): 1478-1489.
  • Guyen GQN, Raulo R, Porquier A, Iacomi B, Pelletier S, Renou JP, Bataillé-Simoneau N, Campion C, Hamon B, Kwasiborski A, Colou J, Benamar A, Hudhomme P, Macherel D, Simoneau P, Guillemette T (2021) Responses of the necrotrophic fungus Alternaria brassisicola to the indolic phytoalexin brassinin. Frontiers in Plant Sciences  11: 1–19.
  • Janse van Rensburg HC, Limami AM, Van den Ende W (2021) Spermine and spermidine priming against Botrytis cinerea modulates ROS dynamics and metabolism in Arabidopsis. Biomolecules 11: 223.
  • Luquet M, Penalver-Cruz A, Satour P, Anton S, Cortesero A-M, Lavandero B, Jaloux B (2021) Aphid honeydew may be the predominant sugar source for Aphidius parasitoids even in nectar-providing intercrops. Biological Controls 158: 104596.
  • Ma WT, Tcherkez G, Wang XM, Schäufele R, Schnyder H, Yang Y, Gong XY (2021) Accounting for mesophyll conductance substantially improves 13C-based estimates of intrinsic water-use efficiency. New Phytologist 229: 1326-1338.
  • Macherel D, Haraux F, Guillou H, Bourgeois O (2021) The conundrum of hot mitochondria. BBA Bioenergetics 1862: 148348.
  • Née G, Châtel-Innocenti G, Meimoun P, Leymarie J, Montrichard F, Satour P, Bailly C, Issakidis-Bourguet E (2021) A new role for plastid thioredoxins in seed physiology in relation with hormone regulation. International Journal of Molecular Sciences 22(19): 10395.
  • Nguyen TT, Planchard N, Dahan J, Arnal N, Balzergue S, Benamar A, Bertin P, Brunaud V, Dargel-Graffin C, Macherel D, Martin-Magniette ML, Quadrado M, Namy O, Mireau H (2021) A case of gene fragmentation in plant mitochondria fixed by the selection of a compensatory restorer of fertility-like PPR gene. Molecular Biology and Evolution 38(8): 3445-3458.
  • Planchet E (2021) Nitric oxide production mediated by nitrate reductase. In Nitric oxide in plant biology. An ancient molecule with emerging roles (Eds: Singh, VJ, Singh S, Tripathi DK, Romero-Puertas M, Sandolio LM), Elsevier Publisher, pp. 111-138.
  • Tcherkez G (2021) How atmospheric oxygen is captured by RuBisCo. Nature Reviews Molecular Cell Biology 22(5): 304.
  • Tcherkez G, Farquhar GD (2021) Rubisco catalytic adaptation is mostly driven by photosynthetic conditions - Not by phylogenetic constraints. Journal of Plant Physiology 267: 153554.
  • Tcherkez G, Papon N (2021) Origin and evolution of photosystems: Lessons from green sulfur bacteria. ChemPhotoChem 5(5): 418-420.
  • Tea I, De Luca A, Schiphorst AM, Grand M, Barillé-Nion S, Mirallié E, Drui D, Krempf M, Hankard R, Tcherkez G (2021) Stable isotope abundance and fractionation in human diseases. Metabolites 11(6): 370.
  • Wang M, Pérez-Garcia MD, Davière JM, Barbier F, Ogé L, Gentilhomme J, Voisine L, Péron T, Launay-Avon A, Clément G, Baumberger N, Balzergue S, Macherel D, Grappin B, Bertheloot J, Achard P, Hamama L, Sakr S (2021) Outgrowth of the axillary bud in rose is controlled by sugar metabolism and signalling. Journal of Experimental Botany 72: 3044–3060.


  • Avelange-Macherel M-H, Rolland A, Hinault M-P, Tolleter D, Macherel D (2020) The mitochondrial small heat shock protein HSP22 from pea is a thermosoluble chaperone prone to co-precipitate with unfolding client proteins. International Journal of Molecular Sciences 21: 97.
  • Bathellier C, Yu LJ, Farquhar GD, Coote ML, Lorimer GH, Tcherkez G (2020) Ribulose 1,5-bisphosphate carboxylase/oxygenase activates O2 by electron transfer. Proc. Natl Acad. Sci. USA 117: 24234-24242.
  • Ben Hdech D, Aubry C, Alibert B, Beucher D, Prospéri JM, Limami AM, Teulat B (2020) Exploring natural diversity of Medicago truncatula reveals physiotypes and loci associated with the response of seedling performance to nitrate supply. Physiologia Plantarum 170: 227-247.
  • Bosseno M, Lambert A, Beucher D, Le Gleuher M, Aubry C, Pauly N, Montrichard F, Boscari A (2020) A simple method for genetic crossing in Medicago truncatula. In The model of legume Medicago truncatula (Ed: de Brujin FJ), John Wiley & Sons, p1027-1032.
  • Cui J, Lamade E, Tcherkez G (2020) Seed Germination in Oil Palm (Elaeis guineensis Jacq.): A Review of Metabolic Pathways and Control Mechanisms. International Journal of Molecular Sciences 21(12): 4227.
  • Gauthier PPG, Saenz N, Griffin KL, Way D, Tcherkez G (2020) Is the Kok effect a respiratory phenomenon? Metabolic insight using 13C labeling in Helianthus annuus leaves. New Phytologist 228: 1243-1255.
  • Limami AM, Morère-Le Paven M-C (2020) Nitrate signaling pathway via the transporter MtNPF6.8 involves abscisic acid for the regulation of primary root elongation in Medicago truncatula. In The model of legume Medicago truncatula (Ed: de Brujin FJ), John Wiley & Sons, p117-124.
  • Lothier J, Diab H, Cukier C, Limami AM, Tcherkez G (2020) Metabolic responses to waterlogging differ between roots and shoots and reflect phloem transport alteration in Medicago truncatula. Plants 9: 1373.
  • Montrichard F, Frendo P, Rey P, Buchanan B (2020) Role of thioredoxins and NADP-thioredoxin reductases in legume seeds and seedlings. In The model of legume Medicago truncatula (Ed: de Brujin FJ), John Wiley & Sons, p80-91.
  • Nietzel T, Mostertz J, Ruberti C, Wagner S, Moseler A, Fuchs P, Müller-Schüssele S J, Benamar A, Poschet G, Büttner M, Née G, Møller I M, Lillig C H, Macherel D, Finkemeier I, Wirtz M, Hell R, Meyer A J, Hochgräfe F, Schwarzländer M (2020) Redox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germination. Proc. Natl. Acad. Sci. USA 117: 741-751.
  • Porcher A, Guérin V, Montrichard F, Lebrec A,  Lothier J, Vian A (2020) Ascorbate glutathione-dependant H2O2 scavenging is an important process in axillary bud outgrowth in rosebush. Annals of Botany 126: 1049-1062.
  • Tcherkez G, Ben Mariem S, Larraya L, García-Mina JM, Zamarreño AM, Paradela A, Cui J, Badeck FW, Meza D, Rizza F, Bunce J, Han X, Tausz-Posch S, Cattivelli L, Fangmeier A, Aranjuelo I (2020) Elevated CO2 has concurrent effects on leaf and grain metabolism but minimal effects on yield in wheat. Journal of Experimental Botany 71: 5990-6003.
  • Tcherkez G, Carroll A, Abadie C, Mainguet S, Davanture M, Zivy M (2020) Protein synthesis increases with photosynthesis via the stimulation of translation initiation. Plant Science 291: 110352.
  • Teulat B (2020) QTL analyses of seed germination and seedling pre-emergence growth under abiotic stresses in Medicago truncatula. In The model of legume Medicago truncatula (Ed: de Brujin FJ), John Wiley & Sons, p837-848.
  • Wang CD, Fourdin R, Quadrado M, Dargel-Graffin C, Tolleter D, Macherel D, Mireau H (2020) Rerouting of ribosomal proteins into splicing in plant organelles. Proc. Natl. Acad. Sci. USA 117: 29929-29987.
  • Zang L, Morère-Le Paven M-C, Clochard T, Porcher A, Satour P, Mojović M, Vidović M, Limami AM, Montrichard F (2020) Nitrate inhibits primary root growth by reducing accumulation of reactive oxygen species in the root tip in Medicago truncatula. Plant Physiology and Biochemistry 146: 363-373.


  • Abadie C, Tcherkez G (2019) Plant sulphur metabolism is stimulated by phororespiration. Communications Biology 2: 379.
  • Bobille H, Fustec J, Robins RJ, Cukier C, Limami AM (2019) Effect of water availability on changes in root amino acids and associated rhizospere on root exudation of amino acids in Pisum sativum L. Phytochemistry 161: 75-85.
  • Boussardon C, Martin-Magniette M-L, Godin B, Benamar A, Vittrant B, Citerne S, Mary-Huard T, Macherel D, Rajjou L, Budar F (2019) Novel cytonuclear combinations modify Arabidopsis thaliana seed physiology and vigor. Frontiers in Plant Science 10: 32.
  • Domergue J-B, Abadie C, Limami A, Way D, Tcherkez G (2019) Seed quality and carbon primary metabolism. Plant Cell & Environment 42: 2776-2788.
  • Havird JC, Noe GR, Link L, Torres A, Logan DC, Sloan DB, Chicco AJ (2019) Do angiosperms with highly divergent mitochondrial genomes have altered mitochondrial function? Mitochondrion 49: 1-11.
  • Philippe F, Verdu I, Morère-Le Paven M-C, Limami AM, Planchet E (2019) Involvement of Medicago truncatula glutamate receptor-like channels in nitric oxide production under short-term water deficit stress. Journal of Plant Physiology 236: 1-6.
  • Réthoré E, d'Andrea S, Benamar A, Cukier C, Tolleter D, Limami AM, Avelange-Macherel M-H, Macherel D (2019) Arabidopsis seedlings display a remarkable resilience under severe mineral starvation using their metabolic plasticity to remain self-sufficient for weeks. The Plant Journal 99: 302-315.
  • Tcherkez G, Limami AM (2019) Net photosynthetic CO2 assimilation: more than just CO2 and O2 reduction cycles. New Phytologist 223: 520-529.
  • Vega-Mas I, Cukier C, Coleto I, Gonzalez-Murua C, Limami AM, Gonzalez-Moro MB, Marino D (2019) Isotopic labelling reveals the efficient adaptation of wheat root TCA cycle flux modes to match carbon demand under ammonium nutrition. Scientific Reports 9: 8925.


  • Alloing G, Mandon K, Boncompagni E, Montrichard F, Frendo P (2018) Involvement of glutaredoxin and thioredoxin systems in the nitrogen-fixing symbiosis between legumes and rhizobia. Antioxidants 7: 182-198.
  • Avelange-Macherel MH, Candat A, Neveu M, Tolleter D, Macherel D (2018) Decoding the divergent subcellular location of two highly similar paralogous LEA proteins. International Journal of Molecular Sciences 19: 1620.
  • Bobille H, Fustec J, Robins RJ, Cukier C, Limami AM (2018) Amino acid fingerprint in the rhizosphere of Pisum sativum in response to water stress. Aspects of Applied Biology 138: 1-4.
  • Cukier C, Lea PJ, Cañas R, Marmagne A, Limami AM, Hirel B (2018) Labeling maize (Zea mays L.) leaves with 15 NH4+ and monitoring nitrogen incorporation into amino acids by GC/MS analysis. Current Protocols in Plant Biology 3(3): e20073.
  • Le Moigne MA, Guérin V, Furet PM, Billard V, Lebrec A, Spichal L, Roman H, Citerne S, Morvan-Bertrand A, Limami AM, Vian A, Lothier J (2018) Asparagine and sugars are both required to sustain secondary axis elongation after bud outgrowth in Rosa hybrida. Journal of Plant Physiology 222: 17-27.
  • Pontié M, Jaspard E, Papon N, Bouchara J-P, Razafimandimby B, Pillet A, Wang X, Friant C, Mbokou S, Vautrin-Ul C, Chelaghmia M (2018) Enhanced direct oxidation of diclofenac (DCF) at a carbon paste electrode (CPE) modified with cellulose and its biodegradability by Scedosporium dehoogii. Research and Reviews in Electrochemistry 9: 114-128.
  • Satour P, Youssef C, Châtelain E, Ly Vu B, Teulat B, Job C, Job D, Montrichard F (2018) Patterns of protein carbonylation during Medicago truncatula seed maturation. Plant, Cell & Environment 41: 2183-2194.


  • Bosseno M, Lambert A, Beucher D, Aubry C, Le Gleuher M, Pauly N, Montrichard F, Boscari A (2017) Protocole simple de rétrocroisement chez Medicago truncatula. Le Cahier des Techniques de l’INRA (92).
  • Cañas RA, Yesbergenova-Cuny Z, Simons M, Chardon F, Armengaud P, Quilleré I, Cukier C, Gibon Y, Limami AM, Nicolas SD, Brulé L, Lea PJ, Maranas CD, Hirel B (2017) Exploiting the genetic diversity of maize using a combined metabolomic, enzyme activity profiling, and metabolic modelling approach to link leaf physiology to kernel yield. The Plant Cell 29: 919-943.
  • Castella C, Mirtziou I, Seassau A, Boscari A, Montrichard F, Papadopoulou K, Rouhier N, Puppo A, Brouquisse R (2017) Post-translational modifications of Medicago truncatula glutathione peroxidase 1 induced by nitric oxide. Nitric Oxide 68: 125-136.
  • Paszkiewicz G, Gualberto JM, Benamar A,   Macherel D, Logan DC (2017) Arabidopsis seed mitochondria are bioenergetically active immediately upon imbibition and specialize via biogenesis in preparation for autotrophic growth. The Plant Cell 29: 109-128.
  • Pellizzaro A, Alibert B, Planchet E, Limami AM, Morère-Le Paven M-C (2017) Nitrate transporters : an overview in legumes. Planta 246: 585-595.
  • Péron T, Candat A, Montiel G, Veronesi C, Macherel D, Delavault P, Simier P (2017) New insights into phloem unloading and expression of sucrose transporters in vegetative sinks of the parasitic plant Phelipanche ramosa L. (Pomei). Frontiers in Plant Science 7: 2048.
  • Planchet E, Lothier J, Limami AM (2017) Hypoxic respiratory metabolism in plants: reorchestration of nitrogen and carbon metabolisms. In Plant respiration : metabolic fluxes and carbon balance, Advances in photosynthesis and respiration (Eds: Tcherkez G, Ghashghaie J.), Springer International Publishing, 43: 209-226.
  • Raveneau MP, Benamar A, Macherel D (2017) Water content, adenylate kinase, and mitochondria drive adenylate balance in dehydrating and imbibing seeds. Journal of Experimental Botany 68: 3501-3512.
  • Ribeiro CW, Baldacci-Cresp F, Pierre O, Larousse M, Benyamina S, Lambert A, Hopkins J, Castella C, Cazareth J, Alloing G, Boncompagni E, Couturier J, Mergaert P, Gamas P, Rouhier N, Montrichard F, Frendo P (2017) Regulation of differentiation of nitrogen-fixing bacteria by microsymbiont targeting of plant thioredoxin s1. Current Biology 27: 1-7.
  • Wakim J, Goudenege D, Perrot R, Gueguen N, Desquiret-Dumas V, Chao de la Barca JM, Rosa ID, Manero F,Le Mao M, Chupin S, Chevrollier A, Procaccio V, Bonneau D, Logan DC, Reynier P, Lenaers G, Khiati S (2017) CLUH couples mitochondrial distribution to the energetic and metabolic status. Journal of Cell Science 130: 1940-1951.


  • Antonio C, Päpke C, Rocha M, Diab H, Limami AM, Obata T, Fernie AR, van Dongen JT (2016) Regulation of primary metabolism in response to low oxygen availability as revealed by carbon and nitrogen isotope redistribution. Plant Physiology 170: 43-56.
  • Bobille H, Limami AM, Robins RJ, Cukier C, Le Floch G, Fustec J (2016) Evolution of the amino acid fingerprint in the unsterilized rhizosphere of a legume in relation to plant maturity. Soil Biology and Biochemistry 101: 226-236.
  • Dell’Aglio E, Salvi D, Kraut A, Baudet M, Macherel D, Neveu M, Ferro M, Curien G, Rolland D (2016) No plastidial calmodulin-like proteins detected by two targeted mass-spectrometry approaches and GFP fusion proteins. New Negatives in Plant Science 3: 19-26.
  • Diab H, Limami AM (2016) Reconfiguration of N Metabolism upon Hypoxia Stress and Recovery: Roles of Alanine Aminotransferase (AlaAT) and Glutamate Dehydrogenase (GDH). Plants 5: 5.
  • Dumas AN, Taconnat L, Barbas E, Rigaill G, Catrice O, Bernard D,  Benamar A, Macherel D, El Amrani A, Berthomé R (2016) Unraveling the early molecular and physiological mechanisms involved in response to phenanthrene exposure. BMC Genomics 17: 818.
  • Jaspard D, Hunault G (2016)  sHSPdb: a database for the analysis of small Heat Shock Proteins. BMC Plant Biology 16: 135.
  • Slama I, Jdey A, Rouached A, Talbi O, Debez A, Ghnaya T, Limami AM, Abdelly C (2016) Comparative responses to water deficit stress and subsequent recovery in the cultivated beet Beta vulgaris and its wild relative B. macrocarpa. Crop and Pasture Science 67: 553-562.
  • Youssef C, Aubry C, Montrichard F, Beucher D, Juchaux M, Ben C, Prosperi J-M, Teulat B (2016) Cell length instead of cell number becomes the predominant factor contributing to hypocotyl length genotypic differences under abiotic stress in Medicago truncatula. Physiologia Plantarum 156: 108-124.


  • Allorent G, Osorio S, Ly Vu J, Falconet D, Jouhet J, Kuntz M, R. Fernie AR, Lerbs-Mache S, Macherel D, Courtois F, Finazzi G (2014) Adjustments of embryonic photosynthetic activity modulate seed fitness in Arabidopsis thalianaNew Phytologist 205: 707-719.
  • Avelange-Macherel M-H,  Payet N, Lalanne D, Neveu M, Tolleter D, Burstin J, Macherel D (2015) Variability within a pea core collection of LEAM and HSP22, two mitochondrial seed proteins involved in stress tolerance. Plant, Cell & Environment 38: 1299-1311.
  • Calmes B, Nguyen G, Dumur J, Agusti-Brisach C, Campion C, Iacomi B, Pigné S, Dias E, Macherel D, Guillemette T, Simoneau P (2015) Glucosinolate-derived isothiocyanates impact mitochondrial function in fungal cells and elicit an oxidative stress response necessary for growth recovery. Frontiers in Plant Science 6: 414.
  • Ekanayake S. B., El Zawily A.M., Paszkiewicz F.G., Rolland A., Logan D.C. 2015. Imaging and analysis of mitochondrial dynamics in living cells. In Plant Mitochondria, Methods and protocols, Methods in Molecular Biology (Eds: Whelan J & Murchia M.W.), Springer protocols, 1305, ISBN 978-1-4939-2639-8.
  • Lahaye M, Falourd X, Limami A, Foucat L (2015) Water mobility and microstructure evolution in the germinating Medicago truncatula seed by NMR relaxometry. A revisited interpretation of multicomponent relaxation. Journal of Agricultural and Food Chemistry 63: 1698-1710.
  • Pellizzaro A, Clochard T, Planchet E, Limami AM, Morère-Le Paven M-C (2015) Identification and molecular characterization of Medicago truncatula NRT2 and NAR2 families. Physiologia Plantarum 154: 256-269.
  • Planchet E., Limami A.M., 2015. Amino acid synthesis under abiotic stress. In Amino acids in higher plants (Eds: D'Mello J.P.F), CAB International, Wallingford, UK., 262-276.
  • Sechet J, Roux C, Plessis A, Effroy D, Frey A, Perreau F, Krieger-Liszkay A, Macherel D, North HM, Mireau H, Marion-Poll A (2015) The ABA-deficiency suppressor locus HAS2 encodes the PPR protein LOI1/MEF11 involved in mitochondrial RNA editing. Molecular Plant 8: 644-656.
  • Wagner S, Smrutisanjita B, De Bortoli S, Logan DC, Fuchs P, Carraretto L, Teardo E, Cendron L, Nietzel T, Fubl M, Doccula FG, Navazio L, Fricker MD, Van Aken O, Finkemeier I, Meyer AJ, Szabo I, Costa A, Schwarzlander M (2015) The EF-hand Ca2+ binding protein MICU choreographs mitochondrial Ca2+ dynamics in Arabidopsis. The Plant Cell 27: 3190-3212.


  • Candat A, Paszkiewicz G, Neveu M, Gautier R, Logan DC, Avelange-Macherel M-H, Macherel D (2014) The ubiquitous distribution of LEA proteins across cell compartments offers tailored protection against abiotic stress. The Plant Cell 26: 3148-3166.
  • Chentli A, Gillmann L, Bouazza L, Medjkal S, Limami AM, Morère-Le Paven M-C, Bousseboua H (2014) Effects of secondary compounds from cactus and acacias trees on rumen microbial profile changes performed by Real-Time PCR. International Journal of Advanced Research 2: 660-671.
  • Dahan J, Tcherkez G, Macherel D, Benamar A, Belcram K1, Quadrado M, Arnal N, Mireau H (2014) Disruption of the CYTOCHROME C OXIDASE DEFICIENT 1 gene leads to cytochrome c oxidase depletion and reorchestrated respiratory metabolism in Arabidopsis thaliana. Plant Physiology 166: 1788-1802.
  • El Zawily AM, Schwarzländer M, Finkemeier I, Johnston IG, Benamar A, Cao Y, Gissot C, Meyer AJ, Wilson K, Datla R, Macherel D, Jones NS, Logan DC (2014) FRIENDLY regulates mitochondrial distribution, fusion, and quality control in Arabidopsis. Plant Physiology 166: 808-828.
  • Jaspard E, Hunault G (2014) Comparison of amino acids, physico-chemical properties and usage of late embryogenesis abundant proteins, Hydrophilins and WHy Domain. PLoS One 9, e109570.
  • Larrainzar E, Molenaar JA, Wienkoop S, Gil-Quintana E, Alibert B, Limami AM, Arrese-Igor C, González EM (2014) Drought stress provokes the down-regulation of methionine and ethylene biosynthesis pathways in Medicago truncatula roots and nodules. Plant, Cell & Environment 37: 2051-2063.
  • Léran S, Varala K, Boyer J-C, Chiurazzi M, Crawford N, Daniel-Vedèle F, David L, Dickstein R, Fernandez E, Forde B, Gassmann W, Geiger D, Gojon A, Gong J-M, Halkier BA, Harris JM, Hedrich R, Limami AM, Rentsch D, Seo M, Tsay Y-F, Zhang M, Coruzzi G, Lacombe B (2014) A unified nomenclature of NITRATE TRANSPORTER 1 / PEPTIDE TRANSPORTER family members in plants. Trends in Plant Science 19: 5-9.
  • Limami AM (2014) Adaptations of nitrogen metabolism to oxygen deprivation in plants. In Low-Oxygen Stress in Plants, Plant Cell Monographs 21 (Eds: van Dongen JT and Licausi F), DOI 10.1007/978-3-7091-1254-0 11; Springer-Verlag, Wien.
  • Limami AM, Diab H, Lothier J (2014). Nitrogen metabolism in plants under low oxygen stress. Planta 239: 531-541.
  • Pellizzaro A, Clochard T, Cukier C, Bourdin C, Juchaux M, Montrichard F, Thany S, Raymond V, Planchet E, Limami AM, Morère-Le Paven M-C (2014) The nitrate transporter MtNPF6.8 (MtNRT1.3) transports ABA and mediates nitrate regulation of primary root growth in Medicago truncatula. Plant Physiology 166: 2152-2165.
  • Pierre J, Teulat B, Juchaux M, Mabileau G, Demilly D, Dürr C. (2014). Cellular changes during Medicago truncatula hypocotyl growth depend on temperature and genotype. Plant Science 217-218:18-26.
  • Planchet E, Verdu I, Delahaie J, Cukier C, Girard C, Morère-Le Paven M-C, Limami AM (2014) Abscisic acid-induced nitric oxide and proline accumulation in independent pathways under water deficit stress during seedling establishment in Medicago truncatula. Journal of Experimental Botany 65: 2161-2170.
  • Schwarzländer M, Wagner S, Ermakova YG, Belousov VV, Radi R, Beckman JS, Buettner GR, Demaurex N, Duchen MR, Forman HJ, Fricker MD, Gems D, Halestrap AP, Halliwell B, Jakob U, Johnston IG, Jones NS, Logan DC, Morgan B, Müller FL, Nicholls DG, Remington SJ, Schumacker PT, Winterbourn CC, Sweetlove LJ, Meyer AJ, Dick TP, Murphy MP (2014) The 'mitoflash' probe cpYFP does not respond to superoxide. Nature 574, E12-E14.


  • Benamar A, Pierart A, Baecker V, Avelange-Macherel M-H,  Rolland A, Gaudichon S, di Gioia L, Macherel D (2013) A simple system using natural mineral water for high-throughput phenotyping of Arabidopsis thaliana seedlings in liquid culture. International Journal of High-throughput Screening 4: 1-15.
  • Benarbia MA, Macherel D, Faure S, Jaques C, Andriantsitohaina R, Malthiery Y (2013) Plasmatic concentration of organochlorine lindane acts as metabolic disruptors in HepG2 liver cell line by inducing mitochondrial disorder. Toxicology and Applied Pharmacology 272: 325-332.
  • Candat A, Poupart P, Andrieu JP, Chevrollie A,  Reynier P, Rogniaux H, Avelange-Macherel M-H,  Macherel D (2013) Experimental determination of organelle targeting peptide cleavage sites using transient expression of GFP translational fusions. Analytical Biochemistry 434: 44-51.
  • Charrier A, Lelièvre E, Limami AM, Planchet E (2013) Medicago truncatula stress associated protein 1 gene (MtSAP1) overexpression confers tolerance to abiotic stress and impacts proline accumulation in transgenic tobacco. Journal of Plant Physiology 170: 874-877
  • Chatelain E, Satour P, Laugier E, Ly Vu B, Payet N, Rey P, Montrichard F (2013) Evidence for participation of the methionine sulfoxide reductase repair system in plant seed longevity. Proc. Natl. Acad. Sci. USA 110: 3633-3638.
  • Diab H, Cukier C (2013) Impact of waterloging-induced hypoxia on nitrogen metabolism in the legume Medicago truncatula. International Journal of Life Sciences Biotechnology and Pharma Research 2: 401-409.
  • Macherel D (2013) We become more aware of the void as we explore it. New Phytologist 199: 873-875.
  • Macherel D, Jaspard E, Candat A, Hunault G, Poupart P, Rolland A, Benamar A, Avelange-Macherel M-H (2013) Why so many LEA proteins? Cryobiology and Cryotechnology 59: 35-39.
  • Rouached A, Slama I, Zorrig W, Jdeya A, Cukier C, Rabhi M, Talbi O, Limami AM, Abdelly C (2013). Differential performance of two forage species: Medicago truncatula and Sulla carnosa under water deficit stress and recovery. Crop and Pasture Science 64: 254-264.


  • Charrier A, Planchet E, Cerveau D, Gimeno-Gilles C, Verdu I, Limami AM, Lelievre E (2012) Overexpression of a Medicago truncatula Stress Associated Protein gene (MtSAP1) leads to nitric oxide accumulation and confers osmotic and salt stress tolerance in transgenic tobacco. Planta 236: 567-577.
  • Jaspard E, Macherel D, Hunault G (2012) Computational and statistical analyses ofamino acid usage and physico-chemical properties of the twelve late embryogenesis abundant protein classes. PloS One 7: e36968.
  • Lechat M-M, Pouvreau J-B, Thoiron S,  Péron T, Gauthier M, Montiel G, Véronési C, Todoroki Y, Monteau F, Macherel D, Simier P, Delavault P (2012) PrCYP707A1, an ABA catabolic gene, is a key component of Phelipanche ramosa seed germination in response to the strigolactone analog GR24. Journal of Experimental Botany 63: 5311-5322.
  • Ren M, Venglat P, Qiu S, Feng L, Cao Y, Wang E, Xiang D, Wang J, Alexander D, Chalivendra S, Logan D, Mattoo A, Selvaraj G, Datla R (2012) Target of rapamycin signaling regulates metabolism, growth, and life span in Arabidopsis. The Plant Cell  24: 4850-4874.
  • Schwarzländer M, Logan DC, Johnston IG, Jones NS, Meyer AJ, Fricker MD, Sweetlove LJ (2012) Pulsing of membrane potential in individual mitochondria: a stress-induced mechanism to regulate respiratory bioenergetics in Arabidopsis. The Plant Cell  24: 1188-1201.
  • Schwarzländer M, Murphy MP,  Duchen MR, Logan DC, Fricker MD, Halestrap AP, Müller FL, Rizzuto R, Dick TP, Meyer AJ, Sweetlove LJ (2012) Mitochondrial ‘flashes’: a radical concept repHined. Trends in Cell Biology 22: 503-508.
  • Zoumarou-Wallis N, Teulat-Merah B, Zinsou V, Ben Salem M, Rhoma S (2012) Detection of the Quantitative Trait Locus (QTL) involved in the resistance of barley (Hordeum vulgare L.) to the mildew under different water treatments, in semi-arid Mediterranean region. International Journal of Science and Advanced Technology 2: 136–143.


  • Dias PMB, Brunel S, Wagner MH, Huguet T, Prospéri J-M, Dürr C, Teulat-Merah B (2011) QTL analyses of germination and pre-emergence growth at extreme temperatures in Medicago truncatula.Theoretical Applied Genetics 122:429-444.
  • Gimeno-Gilles C, Gervais ML, Planchet E, Satour P, Limami AM, Lelievre E (2011) A stress-associated protein containing A20/AN1 zing-finger domains expressed in Medicago truncatula seeds. Plant Physiology and Biochemistry 49: 303-310.
  • Kaiser WM, Planchet E, Rümer S (2011) Nitrate reductase and nitric oxide. In Annual Plant reviews, Nitrogen metabolism in plants in the post-genomic era (Eds: Foyer C and Zhang H), 42: 127-145, DOI: 10.1002/9781444328608.ch6; Wiley-Blackwell, Oxford, UK.
  • Morère-Le Paven M-C, Viau L, Hamon A, Vandecasteele C, Pellizzaro A, Bourdin C, Laffont C, Lapied B, Lepetit M, Frugier F, Legros C, Limami AM (2011)  Characterization of a dual affinity nitrate transporter MtNRT1.3 in the model legume Medicago truncatula. Journal of Experimental Botany 62: 5595–5605.
  • Planchet E, Rannou O, Ricoult C, Limami AM (2011) Unravelling the involvement of ABA in the water deficit-induced modulation of nitrogen metabolism in Medicago truncatula seedlings. Plant Signaling & Behavior 6: 1074-1076.
  • Planchet E, Rannou O, Ricoult C, Boutet-Mercey S, Maia-Grondard A, Limami AM (2011) Nitrogen metabolism responses to water deficit act through both abscisic acid (ABA)-dependent and independent pathways in Medicago truncatula during post-germination. Journal of Experimental Botany 62: 605-615.
  • Renard M, Alkhalfioui F, Schmitt-Keichinger C, Ritzenthaler, Montrichard F (2011) Identification and characterization of thioredoxin h isoforms differentially expressed in germinating seeds of the model legume Medicago truncatula. Plant Physiology 155: 1113-1126.
  • Teulat-Merah B, Morère-Le Paven M-C, Ricoult C, Aubry C, Peltier D (2011) cDNA-AFLP profiling in embryonic axes during the germination time-course has allowed to identify mRNAs associated with early radicle growth in common bean. Biologia Plantarum 55: 437-447.
  • Vandecasteele C, Teulat-Merah B, Morère-Le Paven M-C, Leprince O, Ly Vu B, Viau L, Ledroit L, Pelletier S, Payet N, Satour P, Lebras C, Gallardo K, Huguet T, Limami AM, Prosperi J-M, Buitink J (2011) QTL analysis reveals a correlation between the ratio of sucrose/raffinose family oligosaccharides and seed vigour in Medicago truncatula. Plant, Cell and Environment 34: 1473-1487.


  • Bolingue W, Rosnoblet C, Ly Vu B, Leprince O, Aubry C, Buitink J (2010) The MtSNF4b subunit of the sucrose non-fermenting-related kinase complex connects after-ripening and constitutive defense responses in seeds of Medicago truncatula. The Plant Journal 61: 792-803.
  • Cassan L, Moreau L, Segouin S, Bellamy A, Falque M, Limami AM (2010) Genetic map construction and quantitative trait loci (QTL) mapping for nitrogen use efficiency and its relationship with productivity and quality of the biennial crop Belgian endive (Cichorium intybus L.). Journal of Plant Physiology 167: 1253–1263.
  • Hunault G, Jaspard E (2010) LEAPdb: a database for the late embryogenesis abundant proteins. BMC Genomics 11: 221.
  • Tolleter D, Hincha DK, Macherel D (2010) A mitochondrial late embryogenesis abundant protein stabilizes model membranes in the dry state. BBA Biomembranes 1798: 1926-1933.
  • Tunnacliffe A, Hincha DK, Leprince O, Macherel D (2010) LEA proteins: versatility of forms and function. Lubzens, E., Cerda, J. and M. Clark. Eds. Dormancy and Resistance in Harsh Environments. Topics in Current Genetics, Springer, pp. 91-108.