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Dernière mise à jour : Mai 2018

Menu Logo Principal Agrocampus Ouest Angers University   IRHS

IRHS

Bioinformatics for plant DEFense Investigation

BIDefI

Bioinformatics for plant Defense Investigations
The BioInformatics for plants Defense Investigation (BIDefI) team gathers skills in computing, database development, server administration, ontology, gene evolution and omics data analysis.

The response of plants to the constraints of their environment involves a great diversity of molecular actors. Among them, phytocytokines, also called peptide hormones, are involved in intercellular signaling to initiate or amplify a defense reaction or to control the development of plants. Faced with the challenges of climate change and the sustainable management of plant health, the discovery and characterization of new families of phytocytokines is an interesting avenue of innovation because these peptides have a strong potential for environmentally friendly biocontrol solutions. .Our approach consists of a combined exploratory analysis of the large number of omics data available in international databases. We have recently discovered and identified a new family of small peptides in the model plant Arabidopsis thaliana. Thanks to the experimental validations carried out by our collaborators, within the institute but also at the national or international level, we will enrich and improve our models with the objective of predicting analogues of these phytocytokines in other species of agronomic interest. or conversely peptides specific to a plant species.

Our scientific theme is the defense of plants against biotic and abiotic stresses, our research is organized around two axes:

  1. The identification of phytocytokines involved in the control of plant development and / or in defense control mechanisms with the objective of discovering biocontrol tools.
  2. Understanding the evolutionary dynamics of gene families in Rosaceae genomes including the role of transposable elements and epigenetics in the expansion of gene families and / or the adaptation of plants to environmental stresses.

In addition, since it creation, members of our team have provided bioinformatics support to the unit:

  • administration of the unit's storage and scientific computing infrastructure,
  • development of databases to manage metadata of experiments and cultures carried out at the IRHS,
  • implementation of large-scale data analysis and visualization methods,
  • development of new tools to perform meta-analyzes,
  • technical support for the use of servers,
  • assistance with expertise for genomic and / or transcriptomic analyzes.
  • This work is carried out within the framework of a set of partnerships and has led to the production of a set of publications.